The novel Reach Cage allows neurophysiology studies of structured behavior with unrestrained Rhesus macaques showing that the frontoparietal reach network is selective for reach goals outside the immediately reachable space.
A screen targeting RNA-associated proteins reveals that PSI regulates timeless alternative splicing and thus controls the period of Drosophila circadian behavior and its phase under temperature cycles.
Upon genotoxic stress, the FBXL10-RNF68-RNF2 ubiquitin ligase complex mono-ubiquitylates histone H2A and mediates H2A/H2A.Z exchange to repress transcription and ensures proper high fidelity homologous recombination repair.
Neurons in the midbrain superior colliculus of free-flying echolocating bats represent 3D sensory space, and the depth tuning of single neurons is modulated by an animal's active sonar inspection of physical objects in its environment.
Doubletime kinase stabilizes the PER/TIM complex and regulates its transcriptional inhibition function to delay circadian transcriptional activity, helping sustain 24-hour periodicity in the circadian clock.
Despite their extreme morphologies, snakes display a global regulatory strategy of their Hox genes similar to that implemented by mammals with, however, important modifications in enhancer specificity.
Planar cell polarity (PCP) components and myosin show a parallel temporal polarization in the Ciona notochord and the mutual interaction between these proteins is required for proper tissue-wide polarity.