Planar cell polarity (PCP) components and myosin show a parallel temporal polarization in the Ciona notochord and the mutual interaction between these proteins is required for proper tissue-wide polarity.
A direct connection between distinct planar cell polarity systems orients cells, answering long-standing questions regarding the relationship between systems and the orientation of cell polarity.
A computational model, based on single-cell features like contractility and polarizability, quantitatively describes cellular dynamics from the single cell level up to small cohorts and confluent tissues.
A systematic and quantitative investigation showing how highly specific WW domain-mediated protein-protein interaction network is organized in cell growth and polarity.