8,485 results found
    1. Developmental Biology

    TAF7L modulates brown adipose tissue formation

    Haiying Zhou, Bo Wan ... Robert Tjian
    TAF7L acts as a molecular switch that regulates the development of mesenchymal stem cells.
    1. Immunology and Inflammation

    The Opto-inflammasome in zebrafish as a tool to study cell and tissue responses to speck formation and cell death

    Eva Hasel de Carvalho, Shivani S Dharmadhikari ... Maria Leptin
    Manipulating cell death in situ with the temporal and spatial precision of optogenetic tools opens up new avenues for studying inflammation, death and related phenomena, revealing, for example, that epithelial cell death cannot be classified into strictly distinct categories.
    1. Physics of Living Systems
    2. Developmental Biology

    Unified quantitative characterization of epithelial tissue development

    Boris Guirao, Stéphane U Rigaud ... Yohanns Bellaïche
    A new approach measures the respective participations of elementary cell behaviors – such as cell division, intercalation, shape change and death – in the shaping of animal tissues.
    1. Developmental Biology
    2. Plant Biology

    Generation of shape complexity through tissue conflict resolution

    Alexandra B Rebocho, Paul Southam ... Enrico Coen
    Genetic modulation in patterns of tissue conflict play a major role in the development and evolution of shape diversity.
    1. Developmental Biology
    2. Physics of Living Systems

    From local resynchronization to global pattern recovery in the zebrafish segmentation clock

    Koichiro Uriu, Bo-Kai Liao ... Luis G Morelli
    Theory explains how transport of gene expression vortices by cell advection may cause intermingled defective and normal segments along the body axis during resynchronization experiments in the zebrafish segmentation clock.
    1. Cell Biology

    Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model

    Magdalena Kasendra, Raymond Luc ... Katia Karalis
    Combining Organs-on-Chips technology with adult intestinal organoids provides an improved model of human duodenum and a new platform for preclinical drug assessment.
    1. Stem Cells and Regenerative Medicine

    Positional information specifies the site of organ regeneration and not tissue maintenance in planarians

    Eric M Hill, Christian P Petersen
    Homeostatic tissue maintenance can occur at locations distinct from the target sites of organ regeneration planarians.
    1. Developmental Biology
    2. Plant Biology

    Temporal integration of auxin information for the regulation of patterning

    Carlos S Galvan-Ampudia, Guillaume Cerutti ... Teva Vernoux
    Rhythmic centrifugal waves of auxin traveling through the tissue provides high definition positional information to cells that is not only spatial but also temporal.
    1. Cell Biology
    2. Developmental Biology

    Rho1 activation recapitulates early gastrulation events in the ventral, but not dorsal, epithelium of Drosophila embryos

    Ashley Rich, Richard G Fehon, Michael Glotzer
    Spatially and temporally patterned activation of the small GTPase Rho1 indicates that ventral-specific factors contribute to cell- and tissue-level behaviors during ventral furrow formation, the first step in Drosophila gastrulation.
    1. Computational and Systems Biology
    2. Developmental Biology

    Why plants make puzzle cells, and how their shape emerges

    Aleksandra Sapala, Adam Runions ... Richard S Smith
    Puzzle-shape cells in the epidermis of many plants form due to a development constraint based on mechanical forces.

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