Horizon scanning has been used to identify opportunities and risks presented by 20 emerging issues in the field of biological engineering.

A bioengineering approach identifies tissue morphology as an effective variable for controlling the inception of neural organoid morphogenesis via induction of a biomimetic, singular neural rosette tissue cytoarchitecture.

Guidelines governing research into embryos need to be updated in a way that reflects the moral status of synthetic human entities generated using the methods of synthetic biology.

Modelling beta-amyloid deposition in bioengineered human vessels represents a notable advance to further investigate the role of the vasculature in Alzheimer's disease.

A new three-dimensional model of the blood-brain barrier can be used to study processes that are involved in neurodegenerative diseases.

There is no such thing as a representative skeletal muscle tissue, as each member of this family of tissues expresses a specialized mRNA program.

A novel bioengineered human skeletal muscle model with accurate physiological and pharmacological responses may provide a useful tool for preclinical testing.

The views of peers are important when applying for a faculty position, but so are research plans and being a good 'fit'.

The Janelia Research Campus opened its doors 12 years ago: we describe the philosophy underpinning Janelia, the lessons learned, and plans for the future.