1,178 results found
  1. March 2015

    Episode 19: March 2015

    In this episode we hear about herpes, breweries, model organisms, social interactions in rats and traumatic brain injuries in flies.
    1. Epidemiology and Global Health
    2. Medicine
    3. Microbiology and Infectious Disease

    COVID-19: A Collection of Articles

    Edited by Diane M Harper et al.
    eLife has published the following articles on SARS-CoV-2 and COVID-19.
  2. February 2016

    Episode 27: February 2016

    In this episode we hear about midnight snacking, X-ray imaging of fossils, hummingbirds, monkeys gambling and axolotls regenerating.
  3. April 2014

    Episode 11: April 2014

    In this episode we hear about neuropathic pain, gene therapy, insulin production, aging in worms, and how flatworms grow new body parts.
    1. Chromosomes and Gene Expression

    Sustained TNF-α stimulation leads to transcriptional memory that greatly enhances signal sensitivity and robustness

    Zuodong Zhao et al.
    Sustained TNF-α induction consolidates transcriptional memory for faster, stronger, and more sensitive subsequent induction in an active DNA demethylation-dependent manner for memory genes including CALCB, a therapeutic target for migraine.
    1. Medicine
    2. Neuroscience

    Neural signatures of α2-Adrenergic agonist-induced unconsciousness and awakening by antagonist

    Jesus Javier Ballesteros et al.
    Instant performance recovery is possible following general anesthesia-induced unconsciousness using antagonist, and the brain dynamics return abruptly to the awake state without intermediate recovery states.
    1. Neuroscience

    Neural encoding of actual and imagined touch within human posterior parietal cortex

    Srinivas Chivukula et al.
    Single neurons in human posterior parietal cortex encode actual and imagined touch within a shared neural substrate.
    1. Immunology and Inflammation

    LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation

    Jack P Green et al.
    Depletion of LRRC8A provides genetic evidence for the importance of Cl- channels in NLRP3 activation.
    1. Neuroscience

    Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves

    Miriam Schwalm et al.
    Locally recorded calcium events related to slow wave activity show a global cortical fMRI BOLD correlate, establishing a direct relation between a basic neurophysiological signal and the macroscopic perspective of pre-clinical fMRI.
    1. Neuroscience

    Integrated externally and internally generated task predictions jointly guide cognitive control in prefrontal cortex

    Jiefeng Jiang et al.
    The dorsolateral prefrontal cortex integrates concurrent externally and internally generated predictions of task demand to guide information processing, while the medial prefrontal cortex corrects its prediction error based on actual task demand.

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