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A distinct resident macrophage subpopulation that localizes to the adipose stroma and fibrous capsule of the nulliparous mammary gland and to extracellular matrix-enriched stroma surrounding mammary tumors is identified.

IL18R⁺ Tregs constitute a mature thymus-resident population, resistant to thymus involution and endowed with higher capacity to populate the thymus compared to their IL18R^– or IL18R deficient counterparts.

Adult zebrafish Langerhans cells are derived from hematopoietic stem/progenitor cells but not Erythro-myeloid progenitors.

In-depth proteomic analyses of intestinal tissue-resident intraepithelial T lymphocytes reveals how these cells are adapted to the intestinal environment through increased cholesterol and lipid metabolism, tailored metabolic profiles, receptors for interacting with epithelial cells, and tightly regulated signalling pathways.

Macrophage dynamics are fundamentally different between two commonly used inbred mouse strains and differences in local resident cell expansion versus monocyte recruitment determine the outcome of tissue nematode infection.

Reticulon 1A plays a central role not only in cytoskeletal remodeling of resident Langerhans cells but also in their clustering upon Toll-like receptor activation in human skin, suggesting an important role in maintaining tissue homeostasis.

Detailed analysis of the sequence of monocyte differentiation into distinct gut tissue macrophages provides insights into monocyte biology and can serve as a platform for the design of cell therapies.

GDNF receptor-expressing mesenchymal progenitor subpopulation within skeletal muscle responds to peripheral nerve injury by sensing GDNF and secreting BDNF, thereby directly promoting nerve regeneration through facilitating remyelination by Schwann cells.

Repeated antigen encounters alter the transcriptional state and function of lymph node-resident memory CD8⁺ T cells to mediate improved immunity against viral infection.

Adoptive transfer and genetic manipulation revealed a previously unknown sub-population of PLZFhi CCR7+ iNKT cells as precursors for all three iNKT effector subsets in both thymus and periphery in mice.