Monocytes display distinct migratory and functional activity compared to dendritic cells and alveolar macrophages in the lungs.

Macrophages use integrin-dependent 3D movement and cell protrusiveness, which control cell motility and space exploration as a prerequisite for optimal clearance of particles and dead cells by macrophage networks.

Prdm1 (BLIMP1) promotes liver Group 1 ILCs cancer surveillance and preserves functional heterogeneity.

Deregulated cell fate specification pathways, including oncogenic Ras, cause activation of JNK-signaling at contact sites with wild type cells, which drives apoptosis and aberrant cell elimination in a contact-dependent manner.

A previously unrecognized subpopulation of fibroblasts that immediately responded to stimuli from mouse periodontitis models and activated the Toll-like receptor signaling and chemokine expression to guide oral barrier immunity and gingival inflammation was revealed by mouse gingival single-cell transcriptomic atlas.

The causal role of microglia in the acceleration of spine turnover and generation of presynaptic filopodia is directly demonstrated in the adult brain following acute focal synaptic photodamage.

A certain type of primary cancer may cause another second primary cancer which would be of clinical importance to make a personalized screening plan for certain primary cancer patients.

Using long-term in vivo imaging with miniature two-photon microscopy, microglia surveillance is sleep state-dependent and stress-induced in freely behaving mice, regulated by the locus coeruleus-norepinephrine system and β₂-adrenergic receptors signaling.

Cell competition is an important mechanism selecting against aneuploid cells.

The induction of ISG15 during bacterial infection can be independent of Type I Interferons and leads to an increase in the secretion of cytokines known to be critical for bacterial clearance.