42 results found
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Fundamental constraints in synchronous muscle limit superfast motor control in vertebrates

    Andrew F Mead et al.
    Vertebrate superfast muscles employ similar excitation–contraction strategies but distinct myosin heavy chain genes to allow superfast performance, revealing a maximum speed that cannot be overcome without sacrificing neural control.
    1. Neuroscience

    Gap junction-mediated glycinergic inhibition ensures precise temporal patterning in vocal behavior

    Boris P Chagnaud et al.
    Inhibition provides a means for achieving temporal precision for rapid modulation of an acoustic signal in a vertebrate vocal network.
    1. Neuroscience

    General features of the retinal connectome determine the computation of motion anticipation

    Jamie Johnston, Leon Lagnado
    Feedforward inhibition generates motion anticipation by selectively decreasing sensitivity to a stimulus as it moves across the latter part of a retinal ganglion cell's receptive field.
    1. Neuroscience

    Neural activity in a hippocampus-like region of the teleost pallium is associated with active sensing and navigation

    Haleh Fotowat et al.
    Sparse firing in a hippocampus-like structure of the teleost telencephalon is linked to spatial navigation and active sensing.
    1. Neuroscience

    Nanoscale dynamics of synaptic vesicle trafficking and fusion at the presynaptic active zone

    Thirumalini Vaithianathan et al.
    A combination of tethered diffusion of release-ready synaptic vesicles and vesicle-vesicle fusion supports neurotransmitter release at the presynaptic active zone of sensory synapses.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Alternative splicing of coq-2 controls the levels of rhodoquinone in animals

    June H Tan et al.
    The switch from ubiquinone to rhodoquinone synthesis that is required for parasitic helminths to survive in anaerobic host tissues is due to alternative splicing of polyprenyltransferase COQ-2.
  1. Point of View: Science, art, society and Klimt’s University of Vienna paintings

    Alberto E Pereda
    A set of paintings by Gustav Klimt highlights ongoing tensions in the relationships between art, science and society.
    1. Evolutionary Biology

    Myoglobin primary structure reveals multiple convergent transitions to semi-aquatic life in the world's smallest mammalian divers

    Kai He et al.
    Ancestral sequence reconstruction of an essential muscle protein involved in oxygen storage and transport accurately tracks secondary aquatic transitions in a speciose clade of insectivorous mammals.
    1. Evolutionary Biology

    Retinal oxygen supply shaped the functional evolution of the vertebrate eye

    Christian Damsgaard et al.
    Multiple respiratory and vascular mechanisms have recurrently evolved across the vertebrates to alleviate the oxygen diffusion limitations inherent to the morphology of the retina.
    1. Cell Biology
    2. Neuroscience

    Presynaptic morphology and vesicular composition determine vesicle dynamics in mouse central synapses

    Laurent Guillaud et al.
    In central synapses, the mobility and supply of synaptic vesicles are determined by two independent biological factors: the morphological and structural organization of nerve terminals and the molecular signature of vesicles.

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