The development of diverse tooth shapes among vertebrates, from sharks to mammals, is a highly conserved process, utilising a similar dental signalling centre for more than 400 million years.

The nature and extent of developmental variation seen between mouse strains and genetically identical individuals explain why the first upper molar evolves along preferred path in murine rodents.

Analysis of bearded dragon model reveals a novel tooth replacement strategy that demonstrates the critical importance of epithelial patterning, cell migration, and putative stem cell functional specialization in tissue regeneration.

Ezh2 and Arid1a oppose each other to control expression of Cdkn2a to coordinate tooth furcation development and ultimately determine the number of roots in mouse molars.

The accumulation of ferroptotic stress during tooth development has a critical effect on its morphogenesis.

Teeth and dermal odontodes diverge from the same set of founder odontodes, demonstrating they are modified subsets of the same system, and both oral and dermal epithelial have patterning capacity.

Teeth are maintained in two amphibian groups (caecilians and salamanders) but were lost in frogs over 20 times independently, a higher incidence of edentulism than any other major vertebrate group.

The targeted removal of legacy bisphosphonate from the jawbone by competitive equilibrium therapy not only elucidated the pathological mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) but also established a highly translatable therapeutic option for BRONJ.

The tooth shape of sharks and mice are regulated by a similar signaling center despite their teeth having very different geometries.

A comprehensive compendium of myelin proteins in the peripheral nervous system has been created, alongside a method to address molecular diversity of myelin sheaths in health and disease.