563 results found
    1. Developmental Biology
    2. Evolutionary Biology

    The alternative regenerative strategy of bearded dragon unveils the key processes underlying vertebrate tooth renewal

    Lotta Salomies, Julia Eymann ... Nicolas Di-Poï
    Analysis of bearded dragon model reveals a novel tooth replacement strategy that demonstrates the critical importance of epithelial patterning, cell migration, and putative stem cell functional specialization in tissue regeneration.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA

    David S Booth, Yifan Cheng, Alan D Frankel
    The nuclear export receptor Crm1 cooperatively binds its HIV Rev-RRE cargo as a dimer using a species-specific interface that supports viral replication by enhancing nuclear export of HIV RNA.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Self-sperm induce resistance to the detrimental effects of sexual encounters with males in hermaphroditic nematodes

    Lauren N Booth, Travis J Maures ... Anne Brunet
    Nematode hermaphroditism has co-evolved with a self-sperm sensing mechanism that protects hermaphrodites from the detrimental effects of mating with males.
    1. Ecology
    2. Evolutionary Biology

    Tooth fracture frequency in gray wolves reflects prey availability

    Blaire Van Valkenburgh, Rolf O Peterson ... John A Vucetich
    Despite risks of infection and reduced fitness, tooth fracture frequency in gray wolves increases rapidly when prey are scarce because they must consume carcasses more completely.
    1. Evolutionary Biology

    Computed tomographic analysis of the dental system of three Jurassic ceratopsians and implications for the evolution of tooth replacement pattern and diet in early-diverging ceratopsians

    Jinfeng Hu, Catherine A Forster ... Fenglu Han
    The tooth replacement pattern of early-diverging ceratopsians helps to understand the origin of the specialized dental system of ceratopsids and provides new insights to feeding strategy transition.
    1. Genetics and Genomics

    Insulin-like peptides and the mTOR-TFEB pathway protect Caenorhabditis elegans hermaphrodites from mating-induced death

    Cheng Shi, Lauren N Booth, Coleen T Murphy
    Hermaphroditic Caenorhabditis elegans slow the onset of mating-induced death through self-sperm-regulated insulin-like gene expression, which regulates the activity of the IIS/FOXO pathway, mTOR signaling, and the TFEB/HLH-30 transcription factor.
    1. Developmental Biology

    Overburdened ferroptotic stress impairs tooth morphogenesis

    Haisheng Wang, Xiaofeng Wang ... Ling Ye
    The accumulation of ferroptotic stress during tooth development has a critical effect on its morphogenesis.
    1. Physics of Living Systems

    Optical mapping of ground reaction force dynamics in freely behaving Drosophila melanogaster larvae

    Jonathan H Booth, Andrew T Meek ... Malte C Gather
    A new optical approach reveals dynamics of ground reaction forces in Drosophila larvae and opens new avenues for studying the biomechanics of movement in small animals.
    1. Developmental Biology
    2. Genetics and Genomics

    Genome editing enables reverse genetics of multicellular development in the choanoflagellate Salpingoeca rosetta

    David S Booth, Nicole King
    Genome editing in the choanoflagellate Salpingoeca rosetta opens newfound possibilities to functionally probe choanoflagellate genes that may illuminate the origin of their closest relatives, the animals.
    1. Evolutionary Biology

    Rampant tooth loss across 200 million years of frog evolution

    Daniel J Paluh, Karina Riddell ... David C Blackburn
    Teeth are maintained in two amphibian groups (caecilians and salamanders) but were lost in frogs over 20 times independently, a higher incidence of edentulism than any other major vertebrate group.

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