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    1. Cell Biology

    A delta-tubulin/epsilon-tubulin/Ted protein complex is required for centriole architecture

    Rachel Pudlowski, Lingyi Xu ... Jennifer T Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Conformational changes, excess area, and elasticity of the Piezo protein-membrane nanodome from coarse-grained and atomistic simulations

    Sneha Dixit, Frank Noé, Thomas R Weikl
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Microbiology and Infectious Disease

    The Mycobacterium ulcerans toxin mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane to drive skin necrosis

    Louise Tzung-Harn Hsieh, Belinda S Hall ... Rachel E Simmonds
    The secreted toxin mycolactone has severe effects on the cells lining blood vessels that will play a critical role in the development of swelling in Buruli ulcer disease.
    1. Neuroscience

    Mapping the topographic organization of the human zona incerta using diffusion MRI

    Roy AM Haast, Jason Kai ... Jonathan C Lau
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Criterion placement threatens the construct validity of neural measures of consciousness

    Johannes J Fahrenfort, Philippa A Johnson ... Simon van Gaal
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Developmental Biology
    2. Cancer Biology

    Dissecting infant leukemia developmental origins with a hemogenic gastruloid model

    Denise Ragusa, Chun-Wai Suen ... Cristina Pina
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Inadequate
    1. Developmental Biology
    2. Neuroscience

    Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo

    Taro Ichimura, Taishi Kakizuka ... Takeharu Nagai
    Volumetric trans-scale imaging with a subcellular resolution across a wide field-of-view of 1.5 × 1.0 cm2 has been realized, facilitating the analysis of cellular dynamics during embryogenesis and brain function.
    1. Structural Biology and Molecular Biophysics

    Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling

    Nevin K Zacharia, Stefanie Kuhns ... Esben Lorentzen
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    PROTAC-induced Protein Structural Dynamics in Targeted Protein Degradation

    Kingsley Y Wu, Ta I Hung, Chia-en A Chang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Pinging the Hidden Attentional Priority Map: Suppression Needs Attention

    Changrun Huang, Dirk van Moorselaar ... Jan Theeuwes
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
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