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The secreted toxin mycolactone has severe effects on the cells lining blood vessels that will play a critical role in the development of swelling in Buruli ulcer disease.

A remarkable case of the common evolutionary origin of a prominent spider venom component.

Integration of clinical patient data, pathogen information and a multi-omic analysis of the gut microbiome reveals key determinants of disease in C. difficile-colonized patients.

Genome-wide association studies have established staphylococcal pyomyositis as a disease whose pathogenesis depends critically on expression of a single toxin, Panton–Valentine leukocidin.

Life-threatening S. aureus infections emerge from commensal nose bacteria in association with repeatable adaptive evolution.

A single subpopulation of photoreceptors constitutes a shared node in the neural networks that regulate light-dependent maturation of the circadian clock and light-independent refinement of retinal ganglion cell projections to the brain.

Bacterial warfare protein colicin E1 opens its hinge to plug antibiotic efflux pump TolC and potentiate antibiotics.

Development of specific and high-affinity nanobodies to probe the structure of human acid sensing ion channel-1a and as binding modifiers of the toxins PcTx and MitTx1.

Separate genetic pathways mediate longevity, pathogen resistance, and cell-nonautonomous regulation of xenobiotic detoxification in chemosensory defective Caenorhabditis elegans mutants.

Genetic and microscopy analyses identify a programmed cell death mechanism that kills a cell subpopulation in a bacterial biofilm where oxygen is limiting, thereby promoting dispersion of newborn motile cells through the action of DNA released by dead cells.