969 results found
    1. Plant Biology
    2. Evolutionary Biology

    Herbivory-induced volatiles function as defenses increasing fitness of the native plant Nicotiana attenuata in nature

    Meredith C Schuman, Kathleen Barthel, Ian T Baldwin
    A 2-year field study has demonstrated that volatile compounds produced by plants when they are attacked by herbivores act as defenses by attracting predators to the herbivores and increasing the reproduction of the plants.
    1. Neuroscience

    Quantification of gait parameters in freely walking wild type and sensory deprived Drosophila melanogaster

    César S Mendes, Imre Bartos ... Richard S Mann
    Novel imaging experiments suggest that fruit flies modify their neural circuitry for walking at slow, medium and fast speeds, and that proprioception is not essential for coordinated walking.
    1. Microbiology and Infectious Disease

    Strong inter-population cooperation leads to partner intermixing in microbial communities

    Babak Momeni, Kristen A Brileya ... Wenying Shou
    Simulations and experiments on systems containing two different populations of microorganisms show that interactions that benefit at least one of the populations can lead to communities with stable compositions, and that strong cooperation between two populations can lead to communities in which both populations are mixed together.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K+ channel

    Anirban Banerjee, Alice Lee ... Roderick MacKinnon
    Charybdotoxin, a toxin produced by scorpions, blocks a K+ channel by binding in a lock-and-key fashion to the mouth of the channel and presenting a lysine amino group, which serves as a K+ mimic in the selectivity filter.
    1. Cell Biology

    Caveolae internalization repairs wounded cells and muscle fibers

    Matthias Corrotte, Patricia E Almeida ... Norma W Andrews
    Cells repair damage to their outer membranes not by patching them as previously thought, but by using proteins called caveolins to remove the damaged regions by endocytosis.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Slo1 is the principal potassium channel of human spermatozoa

    Nadja Mannowetz, Natasha M Naidoo ... Polina V Lishko
    Potassium ions enter and leave human sperm cells via a calcium-dependent ion channel that is also pH-independent.
    1. Cancer Biology

    BRAF inhibitors suppress apoptosis through off-target inhibition of JNK signaling

    Harina Vin, Sandra S Ojeda ... Kenneth Y Tsai
    The cancer drug vemurafenib has potent off-target effects on JNK signaling that contribute to the development of squamous cell carcinomas in humans and in mice.
    1. Stem Cells and Regenerative Medicine

    A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties

    Jinsuke Nishino, Sunjung Kim ... Sean J Morrison
    A set of genes that are turned on only within time-limited windows—including genes encoding RNA binding molecules, let-7 microRNAs and IMP1—control developmental switches in stem cell properties between fetal development and adulthood.
    1. Biochemistry and Chemical Biology
    2. Ecology

    ABC transporter functions as a pacemaker for sequestration of plant glucosides in leaf beetles

    Anja S Strauss, Sven Peters ... Antje Burse
    A transport protein enables leaf beetle larvae to take up and store plant toxins and use them as part of their own defense strategy.
    1. Neuroscience

    Hypothalamic melanin concentrating hormone neurons communicate the nutrient value of sugar

    Ana I Domingos, Aylesse Sordillo ... Jeffrey M Friedman
    Natural sugars are preferred over artificial sweeteners because of their nutritional content, which is sensed by MCH neurons in the lateral hypothalamus.

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