Adaptational tradeoffs constrain the evolutionary pathways towards antimicrobial resistance, but highly fit mutants are nevertheless likely to arise at any concentration of the drug.
Observational field analyses demonstrate that within a species, variation in animal weapon size corresponds to individual differences in the costs and benefits of weaponry.
Pierrick Bourrat, Guilhem Doulcier ... Katrin Hammerschmidt
A new model describes evolutionary transitions in individuality in terms of tradeoff and tradeoff-breaking events as opposed to changes in the nature of fitness.
Alex H Williams, Cian O'Donnell ... Timothy O'Leary
A simple model of active transport in neurons allows intracellular cargo to find sites of demand using only local signals, but predicts long delays in distributing cargo throughout a dendritic tree.
Brendan Cornwell, Katrina Armstrong ... Stephen R Palumbi
Bleaching-resistant corals are widespread across Palau and concentrated in warmer regions, but this trait is associated with decreased growth which could lead to reduced fitness if it is the only priority of conservation efforts.
Rodrigo Caetano, Yaroslav Ispolatov, Michael Doebeli
Analytical and numerical analyses reveal that the number of coexisting species exceeds the number of resource only for the structurally unstable case of linear tradeoff.
To establish a trade-off between the speed and accuracy of a decision, neurons in lateral intraparietal cortex combine evidence bearing on the decision with a signal that incorporates the cost of time into the decision-making process.