606 results found
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Predictable properties of fitness landscapes induced by adaptational tradeoffs

    Suman G Das, Susana OL Direito ... Joachim Krug
    Adaptational tradeoffs constrain the evolutionary pathways towards antimicrobial resistance, but highly fit mutants are nevertheless likely to arise at any concentration of the drug.
    1. Ecology
    2. Evolutionary Biology

    Tradeoffs explain scaling, sex differences, and seasonal oscillations in the remarkable weapons of snapping shrimp (Alpheus spp.)

    Jason P Dinh, SN Patek
    Observational field analyses demonstrate that within a species, variation in animal weapon size corresponds to individual differences in the costs and benefits of weaponry.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Distinguishing mutants that resist drugs via different mechanisms by examining fitness tradeoffs

    Kara Schmidlin, Sam Apodaca ... Kerry Geiler-Samerotte
    Nearly a thousand diverse adaptive mutants converge into a handful of groups for which fitness responds the same way to environmental change.
    1. Evolutionary Biology

    Tradeoff breaking as a model of evolutionary transitions in individuality and limits of the fitness-decoupling metaphor

    Pierrick Bourrat, Guilhem Doulcier ... Katrin Hammerschmidt
    A new model describes evolutionary transitions in individuality in terms of tradeoff and tradeoff-breaking events as opposed to changes in the nature of fitness.
    1. Computational and Systems Biology
    2. Neuroscience

    Dendritic trafficking faces physiologically critical speed-precision tradeoffs

    Alex H Williams, Cian O'Donnell ... Timothy O'Leary
    A simple model of active transport in neurons allows intracellular cargo to find sites of demand using only local signals, but predicts long delays in distributing cargo throughout a dendritic tree.
    1. Ecology

    Widespread variation in heat tolerance and symbiont load are associated with growth tradeoffs in the coral Acropora hyacinthus in Palau

    Brendan Cornwell, Katrina Armstrong ... Stephen R Palumbi
    Bleaching-resistant corals are widespread across Palau and concentrated in warmer regions, but this trait is associated with decreased growth which could lead to reduced fitness if it is the only priority of conservation efforts.
    1. Neuroscience

    Confidence predicts speed-accuracy tradeoff for subsequent decisions

    Kobe Desender, Annika Boldt ... Tobias H Donner
    Neural coding of previous-trial confidence affects current decision policy.
    1. Evolutionary Biology

    Evolution of diversity in metabolic strategies

    Rodrigo Caetano, Yaroslav Ispolatov, Michael Doebeli
    Analytical and numerical analyses reveal that the number of coexisting species exceeds the number of resource only for the structurally unstable case of linear tradeoff.
    1. Neuroscience

    High-fidelity musculoskeletal modeling reveals that motor planning variability contributes to the speed-accuracy tradeoff

    Mazen Al Borno, Saurabh Vyas ... Scott L Delp
    The speed-accuracy tradeoff could be a consequence of motor planning variability and not exclusively signal-dependent noise, as is currently held.
    1. Neuroscience

    A neural mechanism of speed-accuracy tradeoff in macaque area LIP

    Timothy Hanks, Roozbeh Kiani, Michael N Shadlen
    To establish a trade-off between the speed and accuracy of a decision, neurons in lateral intraparietal cortex combine evidence bearing on the decision with a signal that incorporates the cost of time into the decision-making process.

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