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Cooperation theory and a novel synthetic infection system provides a mechanistic understanding of why a seemingly successful disease management strategy can have devastating consequences for infected hosts.

Genomic associations with lifespan principally reflect heart disease/smoking/dementia but not other cancers, and distinguish lifespan differences of five years between top/bottom deciles of a score derived from DNA alone.

A dimensional approach to psychiatry demonstrates the specificity and generalizability of a neurocognitive marker of compulsive behavior and intrusive thought via large-scale online testing.

Preimplantation screening of embryos using polygenic risk scores may substantially reduce risk for a given complex disease, but this effect depends on several quantifiable factors and raises significant ethical issues.

By considering a new form of social cheat strategy, arms-races-like dynamics between coevolving selfish traits could emerge from the tragedy of the commons and help explain the variations in cheating levels observed in many microbes and eusocial insects.

A computational method for predicting evolutionary pathways to antimicrobial resistance, accounting for how epistatic interactions determine trajectories, is described.

Epigenetic signature of maternal smoking contributes to smaller body size and lower birth weight in newborns of European and South Asian ancestry.

Epigenetic scores for blood protein levels identify those at risk of multiple age-related morbidities, up to 14 years prior to onset.

While predators can clearly reduce mosquito populations by consumption, they can also have non-consumptive effects on mosquito body size and oviposition behavior, and these effects on vector traits can influence infectious disease dynamics.

A reduced tendency to update beliefs in response to positive relative to negative information predict sooner relapse in euthymic bipolar patients.