Browse the search results

Page 2 of 55
    1. Neuroscience

    Functional brain alterations following mild-to-moderate sensorineural hearing loss in children

    Axelle Calcus et al.
    Mild-to-moderate sensorineural hearing loss causes changes in the neurophysiological functioning that emerge during adolescence, as suggested by both cross-sectional and longitudinal designs.
    1. Neuroscience

    Independent representations of ipsilateral and contralateral limbs in primary motor cortex

    Ethan A Heming et al.
    Neural recordings demonstrate how information about the contralateral limb can be isolated from the ipsilateral limb in motor cortex.
    1. Neuroscience

    Functional clustering of dendritic activity during decision-making

    Aaron Kerlin et al.
    In motor cortex pyramidal neurons, diverse task-related signals are distributed throughout the dendritic arbor and compartmentalized by dendritic distance and branching.
    1. Cell Biology

    β-blockers augment L-type Ca2+ channel activity by targeting spatially restricted β2AR signaling in neurons

    Ao Shen et al.
    FRET biosensor-based measurement of cAMP signaling and single-channel recording reveal that β-blockers trigger local activation of adrenergic receptors and calcium channels in primary neurons.
    1. Epidemiology and Global Health
    2. Human Biology and Medicine

    Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria

    Ceereena Ubaida-Mohien et al.
    The changes in the skeletal muscle proteome with age indicate the roots of the decline in muscle function with age.
    1. Neuroscience

    Monosynaptic tracing maps brain-wide afferent oligodendrocyte precursor cell connectivity

    Christopher W Mount et al.
    Oligodendrocyte precursor cells receive brain-wide, circuit-specific intracortical, coritcocortical and thalamocortical synaptic inputs.
    1. Neuroscience

    During hippocampal inactivation, grid cells maintain synchrony, even when the grid pattern is lost

    Noam Almog et al.
    Grid cells lose their hexagonality during hippocampal inactivation, but maintain temporal and spatial synchrony between pairs of cells, implying that hippocampus does not determine phase relations between grid cells.
    1. Plant Biology

    Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID

    Andrea Mair et al.
    Proximity-labeling using engineered biotin ligases TurboID and miniTurbo enables detection of cell-type-specific and low abundance protein complexes and subcellular proteomes in Arabidopsis and other plants.
    1. Neuroscience

    In vivo functional diversity of midbrain dopamine neurons within identified axonal projections

    Navid Farassat et al.
    Midbrain dopamine neurons function according to their axonal projections in the intact brain.
    1. Structural Biology and Molecular Biophysics

    Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of ‘quasi-ordered’ states

    Amanda F Clouser et al.
    Multiple iso-energetic-specific interactions involving the intrinsically-disordered region of sHSP HSPB1 define a quasi-ordered state, providing insights into inherited disease-associated mutations within the region that are thought to be disordered.