Systematically studying the expression, small RNA-binding partners, and loss-of-function phenotypes of all 19 Argonautes uncovers how small RNA regulatory pathways function and interact in Caenorhabditis elegans, a long-standing model for small RNA biology and RNAi.

A project to repeat experiments from high-impact papers in cancer biology did not complete all replications, with challenges ranging from mundane reasons to unexpected methodological issues.

The actomyosin network and phospho-regulation combine to polarize fate determinants at the Drosophila neuroblast cell cortex.

Interaction of small molecule expands the conformational ensemble of alpha synuclein.

A genetic program controlling brain genes across the lifespan specifies a calendar of changes in cells, synapses and behavioural genes thereby timing the onset of mental illnesses which arise in young adults.

Long-term physical exercise had a substantial effect on the plasma proteome, identifying novel exerkines and suggesting CD300LG as a potential link to insulin sensitivity.

Kidney organoids are a high-fidelity system for investigating basement membrane regulation in development and disease.

A machine-learning approach is used to predict 1.35 million interactions for 85% of the human proteome.

High-resolution live imaging reveals how and when the mouse heart first starts to beat during development and how the onset of beating impacts on heart muscle cell maturation and heart formation.

Impact of odor experience on myeloid metabolism and immunity.