421 results found
    1. Microbiology and Infectious Disease

    Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa

    Jiadai Huang, Yue Sun ... Xin Deng
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Developmental Biology
    2. Genetics and Genomics

    Determining the effects of paternal obesity on sperm chromatin at histone H3 lysine 4 tri-methylation in relation to the placental transcriptome and cellular composition

    Anne-Sophie Pepin, Patrycja A Jazwiec ... Sarah Kimmins
    Epigenomic and transcriptomic analysis reveals that paternal obesity influences sperm histone H3 lysine 4 tri-methylation enrichment and placenta gene expression, which in turn negatively impact its development and function in a manner that may contribute to metabolic disease in offspring.
    1. Cell Biology
    2. Neuroscience

    Dilated cardiomyopathy-associated RNA Binding Motif Protein 20 regulates long pre-mRNAs in neurons

    Giulia Di Bartolomei, Raul Ortiz ... Peter Scheiffele
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology

    Atlas of Fshr expression from novel reporter mice

    Hongqian Chen, Hui-Qing Fang ... Peng Liu
    Exploiting the power of the Fshr reporter, the first comprehensive genetic record of the spatial distribution of FSHR expression offers prospects for extensive exploration of FSH-FSHR biology.
    1. Microbiology and Infectious Disease

    DDX3 regulates the cap-independent translation of the Japanese encephalitis virus via its interactions with PABP1 and the untranslated regions of the viral genome

    Chenxi Li, Linjie Zhang ... Yanhua Li
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cancer Biology

    The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells

    Jie Fang, Shivendra Singh ... Jun Yang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Cell Biology
    2. Neuroscience

    Maintenance of neuronal TDP-43 expression requires axonal lysosome transport

    Veronica H Ryan, Sydney Lawton ... Michael E Ward
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms

    Christopher Bell, Lukas Kilo ... Stefanie Ryglewski
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Microbiology and Infectious Disease

    Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis

    Vivian Salgueiro, Jorge Bertol ... Rafael Prados-Rosales
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Evolutionary Biology

    Upstream open reading frames buffer translational variability during Drosophila evolution and development

    Yuanqiang Sun, Yuange Duan ... Jian Lu
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
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