The transition to the aggregative stage of Capsaspora owczarzaki, a close unicellular relative to Metazoa, is associated with significant upregulation of orthologs of genes that are important for multicellularity in metazoans.

A fungal effector secreted by the corn smut pathogen increases the virulence of the pathogen by elevating anthocyanin production and reducing lignification in maize.

Maternal embryonic leucine zipper kinase (MELK) is a new anti-cancer target that is highly selective for basal-like breast cancer.

Inactivation of a multifunctional RNA-binding protein can lead to the acquisition of pro-metastatic phenotypes, possibly by stabilizing large-scale transcriptomic changes that provide a selective advantage during cancer progression.

Metabolic exaptation of an anaplerotic nitrogen cycle between bundle sheath and mesophyll cells may explain the remarkably frequent convergent evolution of C4 photosynthesis.

Genome neighborhood networks provide an efficient large-scale approach to mine metabolic pathway context for entire families of proteins and enzymes.

Dali regulates transcription of the Pou3f3 locus locally and binds and regulates active promoters in trans by modulating DNA methylation status.

Genes associated with age-based division of labor in ants exist in distinct regulatory and evolutionary contexts; genes up-regulated in young nurses are loosely connected and rapidly evolving while genes up-regulated in old foragers are highly connected and conserved.

Genome wide analysis reveals that many transcripts are localized in cells of the ovary and that the localization status of mRNAs changes over time and in different cell types.

Dosage-compensated gene expression facilitates chromosomal aneuploidy, which presents a rapid route to phenotypic evolution in natural yeast isolates.