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    1. Neuroscience

    Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Parkinsonism models

    Ulrike Pech, Jasper Janssens ... Patrik Verstreken
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Multiplexed Assays of Human Disease-relevant Mutations Reveal UTR Dinucleotide Composition as a Major Determinant of RNA Stability

    Jia-Ying Su, Yun-Lin Wang ... Chien-Ling Lin
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Enalapril mitigates aging by targeting antioxidative genes via phosphorylated Smad1/5/9

    Wencong Lyu, Haochen Wang ... Wei Tao
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Evolutionary Biology
    2. Neuroscience

    Shore crabs reveal novel evolutionary attributes of the mushroom body

    Nicholas Strausfeld, Marcel E Sayre
    Dramatic phenotypic divergence of crustacean mushroom bodies map to phylogenetic lineages, thereby offering unexplored opportunities for relating divergent cognitive centers to different ecologies and behavioral repertoires required to negotiate them.
    1. Epidemiology and Global Health

    Sex differences in biological aging with a focus on human studies

    Sara Hägg, Juulia Jylhävä
    Biological aging processes and age-related diseases demonstrate sexual dimorphism where complex interactions between underlying aging mechanisms and sex chromosomes and hormones are seen in humans and animals.
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    R-Spondin Mimetic, SZN-043, Induced Proliferation and Wnt Activity, Two Features Deficient in Human Alcohol-Associated Liver Disease

    Trevor Fisher, Mehaben Patel ... Helene Baribault
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Plant Biology

    Lipid transfer from plants to arbuscular mycorrhiza fungi

    Andreas Keymer, Priya Pimprikar ... Caroline Gutjahr
    Identification of two arbuscular mycorrhiza-specific lipid biosynthesis mutants and fatty acid transfer experiments reveal that host plant lipids are transferred to symbiotic fungi and needed for their development.
    1. Neuroscience

    NeuroSCAN: Exploring Neurodevelopment via Spatiotemporal Collation of Anatomical Networks

    Noelle L Koonce, Sarah E Emerson ... Daniel Colón-Ramos
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Brain-derived exosomal hemoglobin transfer contributes to neuronal mitochondrial homeostasis under hypoxia

    Zhengming Tian, Feiyang Jin ... Jia Liu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Sphingosine-1-phosphate signaling regulates the ability of Müller glia to become neurogenic, proliferating progenitor-like cells

    Olivia Taylor, Nick DeGroff ... Andy J Fischer
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
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