Dcp2 C-terminal domain cis-regulatory elements collaborating with specific activators control decapping enzyme targeting and activation by orchestrating sequential assembly of distinct decapping complexes.

Affinity measurements of microRNA sites representing >1000 different pairing architectures reveal that two binding modes can mediate pairing to the microRNA 3′ region, and that microRNA G and oligo(G/C) residues are most impactful.

A previously unrecognized group of metalloenzymes enables human gut microbes to metabolize dietary molecules and neurotransmitters and likely mediates interactions and metabolism among environmental microorganisms.

Gene expression and epigenetic profiling of defined cell types in the central nervous system of mouse, rat, and human reveals inter-species and inter-individual differences.

miR-31 drives proliferation of intestinal stem cells, and protects intestinal stem cells against apoptosis both during homeostasis and regeneration in response to ionizing radiation injury, and promotes intestinal tumorigenesis through regulation of multiple signaling pathways.

During Kupffer's vesicle morphogenesis, cell volume anisotropy impacts cell shape changes.

During Staphylococcus aureus infections, bacterial cells bifurcate into distinct, specialized cell types that localize physically in different colonization tissues to simultaneously generate different infection types.