58 results found
    1. Neuroscience

    Exposure to high-sugar diet induces transgenerational changes in sweet sensitivity and feeding behavior via H3K27me3 reprogramming

    Jie Yang, Ruijun Tang ... Liming Wang
    Exposure to high-sugar diet in Drosophila resulted in the suppression of sweet sensitivity and feeding behavior in the offspring via altered epigenetic modifications on the histone, highlighting sustained impact of ancestral experience on the physiology and health of offspring.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    Transgenerational inheritance of ethanol preference is caused by maternal NPF repression

    Julianna Bozler, Balint Z Kacsoh, Giovanni Bosco
    Maternally experienced environmental stress leads to multigenerational inheritance of ethanol preference and an altered rewards pathway in Drosophila melanogaster.
    1. Genetics and Genomics
    2. Neuroscience

    Behavioral Inheritance: When mothers leave their mark

    Raquel Barajas-Azpeleta, Kausik Si
    Progeny can inherit parental experiences through altered brain chemistry.
    Version of Record
    Insight
    1. Neuroscience

    Early life stressful experiences escalate aggressive behavior in adulthood via changes in transthyretin expression and function

    Rohit Singh Rawat, Aksheev Bhambri ... Arpita Konar
    Hypothalamic TTR as a novel molecular player of stress-induced long-term impact on behavior.
    1. Computational and Systems Biology

    Heritable epigenetic changes are constrained by the dynamics of regulatory architectures

    Antony M Jose
    A foundation for analyzing epigenetic changes within the context of regulatory architectures that enable heredity.
    1. Microbiology and Infectious Disease

    Host genetic selection for cold tolerance shapes microbiome composition and modulates its response to temperature

    Fotini Kokou, Goor Sasson ... Itzhak Mizrahi
    Microbiome and transcriptomic profiling of genetically selected tropical fish with high and low tolerance to cold exposure revealed host control over microbiome composition and response to temperature changes.
    1. Evolutionary Biology

    A scenario for an evolutionary selection of ageing

    Tristan Roget, Claire Macmurray ... Michael Rera
    Ageing is broadly accepted as a by-product of evolution, as thus, models allowing to conceive ageing as an adaptive force of evolution could show significant importance at a time of biogerontology mostly aiming at curing ageing.
    1. Developmental Biology

    Maternally provided LSD1/KDM1A enables the maternal-to-zygotic transition and prevents defects that manifest postnatally

    Jadiel A Wasson, Ashley K Simon ... David J Katz
    Epigenetic reprogramming by LSD1/KDM1A acts at fertilization in mice to enable embryogenesis and prevent behavioural abnormalities.
    1. Ecology

    Parental effects alter the adaptive value of an adult behavioural trait

    Rebecca M Kilner, Giuseppe Boncoraglio ... Hanna Kokko
    The adaptive value of social behaviour exhibited in adult life varies with conditions experienced in early life, and poorer conditions may promote conflict over cooperation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Nongenetic inheritance and multigenerational plasticity in the nematode C. elegans

    L Ryan Baugh, Troy Day
    Evidence is mounting that environmentally-induced adaptive changes in phenotype can be transmitted across generations, but mechanistic gaps and theoretical concerns must be addressed to impact mainstream views of evolutionary adaptation.

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