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Intergenerational adaptations to stress play a critical role in organismal responses to changing environments and are largely lost or erased after one generation.

Although developing oocytes and sperm of mice both harbor the glucocorticoid receptor, fetal oocytes are resistant to differing levels of gluocorcorticoid stress hormones, while spermatogonia alter RNA splicing.

Predisposition to obesity-associated diseases is dependent on the ancestors' diet.

Maternal obesity mouse model reveal that melatonin deficiency causes the genomic hyper-methylation of oocytes via increasing the expression of DNA methyltransferases.

A quantitative video tracking analysis reveals that to gain the nutrients they need, flies change their decisions to exploit foods with different nutrient contents and explore the environment according to their internal amino acid and reproductive states.

A novel paternal effect based on nicotine exposure reveals that offspring exhibit an adaptive, yet nonspecific, resistance to multiple toxins.

Live-cell microscopy and genome-wide screens reveal how slow transitions in metabolism can underlie metabolic memory, providing a model for organisms demonstrating similar history-dependent behaviour and routes to improve industrial microbes.

Somatic aging and germline RNAi pathways promote inheritance of ancestral starvation memory through reallocation of fat storage in Caenorhabditis elegans.

Transient adaptation to environmental fluctuations in plants is mediated through discrete epigenetic changes.