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The Toll-like receptor 2-4 genetic modification goat improves effectively resistance against Staphylococcus aureus infection by enhancing autophagy level, and it provides a novel strategy for challenge of S. aureus-caused infections.

An endosymbiont transgene in Drosophila melanogaster exhibits remarkable phenotypic sensitivity, including to synonymous codon changes.

A novel genetic strategy for induction of reproducible neural tumors (or any other deleterious phenotype) in a single Drosophila stock (applicable to other organisms).

A novel BAC transgenic mouse model reveals glial restriction of P2X7 expression in the central and peripheral nervous systems.

New transgenic mice, which can be ablated both orexin neurons and MCH neurons, showed new brain state and revealed functional interaction that MCH neurons have protective role in narcolepsy symptoms.

Morphologic, molecular, biomechanical and computational analyses show that the specialized extracellular matrix architecture of the umbilical artery contributes to its rapid closure at birth and regulates smooth muscle cell differentiation.

The method presented here allows researchers to retrieve accurate and reproducible biomechanical properties of mouse cartilage.

Genetic analyses revealed the critical role of local Wnt in neuronal patterning by instructing neurite pruning.

The three-dimensional architecture of the genome in distinct cell types predicts genes and regulatory elements involved in cell function and disease.