Flow cytometric isolation and fate mapping shows that neurosphere-initiating cells are highly mitotically active and persist only transiently in vivo, and are distinct from quiescent, long-lived neural stem cells.
A map of the entire array of cell types and potential projections in the mushroom body of the fruit fly brain provides insights into the circuitry that supports learning of stimulus-reward and stimulus–punishment associations.
A broadly used gene expression regulatory mechanism inactivates targets by CED-3-caspase-mediated proteolysis and works in parallel to miRNAs for diverse non-apoptotic developmental functions.
Large-scale changes in the brain's functional circuitry can be brought about by simple changes in gene expression in neural stem cells during development.
A cell-surface receptor called Gpr52 is able to lower the levels of the disease-causing protein mutant huntingtin and suppress its toxicity when knocked-down, making this receptor a promising drug target in Huntington's disease.
A cell surface receptor called Ret enables neurons to establish and maintain the organized arrays of dendrites that support communication between neurons.
