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    1. Developmental Biology
    2. Genetics and Genomics

    Astrogliosis and neuroinflammation underlie scoliosis upon cilia dysfunction

    Morgane Djebar, Isabelle Anselme ... Christine Vesque
    Brain ventricular astrogliosis and neuroinflammation precede scoliosis onset in the zebrafish rpgrip1l ciliary mutant and anti-inflammatory treatment drastically reduces scoliosis while correcting urotensin related peptide level is ineffective.
    1. Genetics and Genomics

    Identifying in vivo genetic dependencies of melanocyte and melanoma development

    Sarah Perlee, Yilun Ma ... Richard M White
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics

    An in vitro approach reveals molecular mechanisms underlying endocrine disruptor-induced epimutagenesis

    Jake D Lehle, Yu-Huey Lin ... John R McCarrey
    The utility of an in vitro cell culture system for studies of molecular mechanisms underlying the initial induction and subsequent propagation of environmentally induced epimutations is demonstrated.
    1. Neuroscience

    Single dopaminergic neuron DAN-c1 in Drosophila larval brain mediates aversive olfactory learning through D2-like receptors

    Cheng Qi, Cheng Qian ... Daewoo Lee
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    Hexokinase regulates Mondo-mediated longevity via the PPP and organellar dynamics

    Raymond Laboy, Marjana Ndoci ... Adam Antebi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology
    2. Evolutionary Biology

    Differences in size and number of embryonic type-II neuroblast lineages are associated with divergent timing of central complex development between beetle and fly

    Simon Rethemeier, Sonja Fritzsche ... Vera S Hunnekuhl
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Segment-specific axon guidance by Wnt/Fz signaling diversifies motor commands in Drosophila larvae

    Suguru Takagi, Shiina Takano ... Akinao Nose
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    Ribosomal composition affects the noncanonical translation and toxicity of polyglycine-containing proteins in fragile X-associated conditions

    Katarzyna Tutak, Izabela Broniarek ... Krzysztof Sobczak
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Structural Biology and Molecular Biophysics
    2. Genetics and Genomics

    The RNA-binding activity of the TRIM-NHL protein NHL-2 is essential for miRNA-mediated gene regulation

    Nasim Saadat, Rhys N. Colson ... Peter R. Boag
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Somatotopic organization among parallel sensory pathways that promote a grooming sequence in Drosophila

    Katharina Eichler, Stefanie Hampel ... Andrew M Seeds
    A synaptic resolution somatotopic map of nearly all mechanosensory neurons on the Drosophila head that individually elicit aimed grooming of specific head locations and collectively elicit a head grooming sequence.
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