759 results found
    1. Stem Cells and Regenerative Medicine
    2. Immunology and Inflammation

    MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice

    Jimmy L Zhao, Dinesh S Rao ... David Baltimore
    Chronic and excessive inflammation can lead to exhaustion of the supply of hematopoietic stem cells and to myeloid malignancies in mice, mimicking important aspects of the myelodysplastic syndrome found in humans.
    1. Cell Biology

    Intraflagellar transport drives flagellar surface motility

    Sheng Min Shih, Benjamin D Engel ... Ahmet Yildiz
    The transport of proteins along flagellar microtubules generates the force that enables flagella to propel cells across surfaces.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Massive palmitoylation-dependent endocytosis during reoxygenation of anoxic cardiac muscle

    Mei-Jung Lin, Michael Fine ... Donald W Hilgemann
    Reoxygenation of anoxic cardiac tissue promotes massive endocytosis that is triggered by release of coenzymeA from mitochondria, followed by palmitoylation of membrane proteins, sarcolemma vesiculation, and transfer of sarolemma vesicles to large endosomes and vacuoles.
    1. Neuroscience

    Development of schemas revealed by prior experience and NMDA receptor knock-out

    George Dragoi, Susumu Tonegawa
    Novel spatial representations by hippocampal cellular assemblies develop on the framework of preconfigured hippocampal networks whose homeostatic synaptic reorganization is accelerated by prior experience and CA3 NMDAR-dependent plasticity.
    1. Neuroscience

    A diversity of localized timescales in network activity

    Rishidev Chaudhuri, Alberto Bernacchia, Xiao-Jing Wang
    Specific types of heterogeneity in the connectivity profile of a biological network give rise to dynamics with a hierarchy of localized temporal scales.
    1. Neuroscience

    Fast transient networks in spontaneous human brain activity

    Adam P Baker, Matthew J Brookes ... Mark Woolrich
    Non-invasive MEG recordings reveal that patterns of spontaneous activity in the resting brain are shorter lived than previously thought.
    1. Neuroscience

    Criticality and degeneracy in injury-induced changes in primary afferent excitability and the implications for neuropathic pain

    Stéphanie Ratté, Yi Zhu ... Steven A Prescott
    No single molecular change is uniquely necessary to cause neuropathic changes in primary afferent excitability; multiple different changes are sufficient.
    1. Developmental Biology

    Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitors

    Lincoln T Shenje, Peter Andersen ... Chulan Kwon
    Cardiac progenitors remain undifferentiated and expansive in the second pharyngeal arch that serves as a microenvironment, and Numb and Numblike are required for their renewal.
    1. Neuroscience

    Cerebellar modules operate at different frequencies

    Haibo Zhou, Zhanmin Lin ... Martijn Schonewille
    Zebrin-positive cerebellar Purkinje cells fire at lower frequencies than zebrin-negative cells, indicating that cerebellar circuits are not physiologically homogeneous.
    1. Neuroscience

    Atoh1-dependent rhombic lip neurons are required for temporal delay between independent respiratory oscillators in embryonic mice

    Srinivasan Tupal, Wei-Hsiang Huang ... Paul A Gray
    The rhythmic patterns of activity that underlie breathing are generated and coordinated by distinct populations of neurons within the brainstem.

Refine your results by:

Type
Research categories