IL-6 signaling drives fibroblast activation in tendinopathy, emerging as a promising therapeutic target for these increasingly prevalent and costly tendon conditions.
Louise Tzung-Harn Hsieh, Belinda S Hall ... Rachel E Simmonds
The secreted toxin mycolactone has severe effects on the cells lining blood vessels that will play a critical role in the development of swelling in Buruli ulcer disease.
Both genetic and pharmacological studies reveal an essential role for the CRF1 receptor in social behavior deficits induced by a single morphine administration in male, but not in female, mice.