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    1. Microbiology and Infectious Disease

    Host and viral determinants of airborne transmission of SARS-CoV-2 in the Syrian hamster

    Julia R Port, Dylan H Morris ... Vincent J Munster
    An experimental animal model provides further insights into the host and viral mechanisms underlying airborne transmission of SARS-CoV-2.
    1. Epidemiology and Global Health

    Effect of an enhanced public health contact tracing intervention on the secondary transmission of SARS-CoV-2 in educational settings: The four-way decomposition analysis

    Olivera Djuric, Elisabetta Larosa ... The Reggio Emilia Covid-19 Working Group
    Prompt contact tracing (testing at the beginning instead of at the end of isolation period) of individuals with COVID-19 in the community reduces delays in contact tracing, increases identification of source of infection, and reduces transmission rates in educational settings.
    1. Microbiology and Infectious Disease

    Transcriptional regulation of SARS-CoV-2 receptor ACE2 by SP1

    Hui Han, Rong-Hua Luo ... Cheng-Gang Zou
    SP1 serves as an important transcription factor in the regulation of ACE2 expression.
    1. Epidemiology and Global Health

    Antigenic strain diversity predicts different biogeographic patterns of maintenance and decline of antimalarial drug resistance

    Qixin He, John K Chaillet, Frédéric Labbé
    A novel compartment model identifies the impact of malaria strain diversity on biogeographic drug resistance patterns, supported by empirical evidence.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Emerging variants of SARS-CoV-2 NSP10 highlight strong functional conservation of its binding to two non-structural proteins, NSP14 and NSP16

    Huan Wang, Syed RA Rizvi ... Shozeb Haider
    Structure and simulations reveal SARS-CoV-2 NSP10 is more resistant to genetic variations than other SARS-CoV-2 NSPs and that the presence of mutations conserves structural and dynamic changes in NSP10.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Estimating the contribution of subclinical tuberculosis disease to transmission: An individual patient data analysis from prevalence surveys

    Jon C Emery, Peter J Dodd ... Rein MGJ Houben
    Data analysis and mathematical modelling suggest that subclinical tuberculosis contributes substantially to transmission and needs to be diagnosed and treated for effective progress towards tuberculosis elimination.
    1. Microbiology and Infectious Disease
    2. Epidemiology and Global Health

    The inter-continental population dynamics of Neisseria gonorrhoeae

    Magnus N Osnes, Ola B Brynildsrud ... Vegard Eldholm
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Rapid cloning-free mutagenesis of new SARS-CoV-2 variants using a novel reverse genetics platform

    Enja Tatjana Kipfer, David Hauser ... Thomas Klimkait
    CLEVER enables the rapid manipulation and direct rescue of plus-strand RNA viruses with the shortest hands-on time to study viral variants of concern.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Within-host diversity improves phylogenetic and transmission reconstruction of SARS-CoV-2 outbreaks

    Arturo Torres Ortiz, Michelle Kendall ... Louis Grandjean
    The use of within-host pathogen genomic sequence data can be used to improve phylogenetic and transmission estimates.
    1. Medicine
    2. Microbiology and Infectious Disease

    The natural tannins oligomeric proanthocyanidins and punicalagin are potent inhibitors of infection by SARS-CoV-2

    Hsiao-Fan Chen, Wei-Jan Wang ... Mien-Chie Hung
    Two natural tannins, oligomeric proanthocyanidins and punicalagin, acted as potent inhibitors against SARS-CoV-2 infection, and grape seed extract supplementation could serve as a healthy food for infection prevention.