Skin-associated bacteria underlie the production of a potent defensive neurotoxin in newts, impacting host physiology, molecular evolution, and predator-prey interactions in a coevolutionary arms race.
The probability of occupancy of individual synaptic release sites at rest sets an upper limit to synaptic output when increasing action potential related calcium entry.
A trypanosome DYRK kinase that exhibits fundamental differences to conventional DYRK family regulation links parasite quorum sensing, signal transduction and developmental gene expression.
The mouse cerebellum regulates innate defensive neural circuitry by tonically controlling dopamine release in the periaqueductal gray, thereby modulating synaptic responses of the Chx10-positive neurons that generate freezing behavior.
Cell-specific alternative splicing of the synaptic calcium channel gene Cacna1b is controlled by exon hypomethylation and CTCF binding and is disrupted following nerve injury.
Glutamatergic projections from basolateral to central amygdala, implicated in neuropsychiatric disorders, develop rapidly during early postnatal period and their development is modulated via endogenously active kainate receptors.
Dynamic SILAC labeling in combination with mass spectrometry revealed substantial regulation of protein synthesis, degradation, turnover, and abundance during homeostatic scaling in neurons.
