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    1. Neuroscience

    Synaptic transmission parallels neuromodulation in a central food-intake circuit

    Philipp Schlegel et al.
    Connectomic analysis demonstrates that a brain circuit, that may be conserved between flies and mammals, uses both fast synaptic transmission as well as peptidergic neuromodulation to connect chemosensory and endocrine systems.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission

    Jonas Klinkhammer et al.
    Interferon-λ plays a decisive and previously underestimated role in limiting the spread of respiratory viruses from the nasal cavity to the lungs and it efficiently restricts virus transmission from infected individuals to naïve contacts.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Using paired serology and surveillance data to quantify dengue transmission and control during a large outbreak in Fiji

    Adam J Kucharski et al.
    A combination of surveillance data, paired sera and mathematical modelling reveals which factors may influence dengue transmission and control in island settings.
    1. Epidemiology and Global Health

    Variation in natural exposure to anopheles mosquitoes and its effects on malaria transmission

    Wamdaogo M Guelbéogo et al.
    Heterogeneity in exposure to malaria vectors, including sporozoite-infected mosquitoes, contributes to the variation in human infection risk and amplifies the local transmission potential.
    1. Neuroscience

    Dopamine neuron glutamate cotransmission evokes a delayed excitation in lateral dorsal striatal cholinergic interneurons

    Nao Chuhma et al.
    Dopamine neurons make novel glutamatergic connections to striatal cholinergic interneurons in the lateral dorsal striatum that are mediated by metabotropic glutamate receptors coupled to TrpC channels.
    1. Microbiology and Infectious Disease

    Sexual transmission of murine papillomavirus (MmuPV1) in Mus musculus

    Megan E Spurgeon, Paul F Lambert
    MmuPV1, a papillomavirus that infects laboratory mice (Mus musculus), is discovered to be sexually transmitted, providing a new animal virus model to study sexually transmitted human papillomaviruses (HPVs).
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    A transmission-virulence evolutionary trade-off explains attenuation of HIV-1 in Uganda

    François Blanquart et al.
    Analysis of epidemiological data reveals that viral loads in newly HIV-1 infected individuals in Uganda have declined for two decades, and evolutionary modelling shows that attenuation of the virus explains this decline.
    1. Microbiology and Infectious Disease

    Impact of HIV co-infection on the evolution and transmission of multidrug-resistant tuberculosis

    Vegard Eldholm et al.
    HIV co-infection does not affect Mycobacterium tuberculosis mutation rates and does not drive the emergence of antimicrobial resistance within patients in the largest outbreak of multidrug-resistant tuberculosis in Latin America to date.
    1. Neuroscience

    Functional connectivity in human auditory networks and the origins of variation in the transmission of musical systems

    Massimo Lumaca et al.
    Resting-state functional connectivity between core regions of fronto-temporal auditory networks can distinguish music transmitters from innovators.
    1. Developmental Biology
    2. Neuroscience

    Adult-born neurons modify excitatory synaptic transmission to existing neurons

    Elena W Adlaf et al.
    The formation of new neurons in the adult dentate gyrus causes a proportion of cortical neurons to transfer their existing connections to the newborn cells.