334 results found
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Synergy in anti-malarial pre-erythrocytic and transmission-blocking antibodies is achieved by reducing parasite density

    Ellie Sherrard-Smith et al.
    Combining pre-erythrocytic and transmission blocking antibodies enhances the overall control and potential elimination of malaria within both mosquito and vertebrate populations.
    1. Microbiology and Infectious Disease

    Malaria: On a mission to block transmission

    Amanda Ross, Nicolas MB Brancucci
    The controlled infection of volunteers with Plasmodium falciparum parasites could provide a platform to evaluate new drugs and vaccines aimed at blocking malaria transmission.
    Insight
    Available as:
    • HTML
    • PDF
    1. Epidemiology and Global Health
    2. Medicine

    Conjunction of factors triggering waves of seasonal influenza

    Ishanu Chattopadhyay et al.
    Three complementary computational approaches reveal a set of putative causes of initiation of pan-USA waves of influenza.
    1. Microbiology and Infectious Disease

    A live attenuated-vaccine model confers cross-protective immunity against different species of the Leptospira genus

    Elsio A Wunder et al.
    A single dose of a characterized motility-deficient mutant was sufficient to induce robust anti-protein antibodies' response and cross-protective immunity against death and colonization in two different animal models of leptospirosis.
    1. Epidemiology and Global Health
    2. Medicine

    Estimates of the global burden of Japanese encephalitis and the impact of vaccination from 2000-2015

    Tran Minh Quan et al.
    Modelling analysis reveals the burden of Japanese Encephalitis is greater than previously thought, and although vaccination has reduced burden, there are remaining places with a great need for vaccination.
    1. Epidemiology and Global Health

    Opportunities for improved surveillance and control of dengue from age-specific case data

    Isabel Rodriguez-Barraquer et al.
    Age-specific incidence data, combined with mechanistic models of immunity, provides a unique opportunity to characterize disease transmission of dengue and other immunizing diseases at high temporal and spatial resolution.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    The intractable challenge of evaluating cattle vaccination as a control for bovine Tuberculosis

    Andrew James Kerr Conlan et al.
    Natural transmission experiments should be prioritised over risky and expensive field trials, in order to establish the impact of cattle vaccination on the transmission of bovine Tuberculosis.
    1. Microbiology and Infectious Disease
    2. Medicine

    A randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection model

    Isaie J Reuling et al.
    Controlled human malaria infection model allows the study of gametocyte biology and dynamics providing novel insights and tools in malaria transmission and elimination efforts.
    1. Microbiology and Infectious Disease

    Transgenic shRNA pigs reduce susceptibility to foot and mouth disease virus infection

    Shengwei Hu et al.
    A transgenic small hairpin RNA can provide a viable tool for enhancing resistance to viral infection in livestock and improve animal well-being.
    1. Neuroscience

    Medium spiny neurons activity reveals the discrete segregation of mouse dorsal striatum

    Javier Alegre-Cortés et al.
    Analysis of slow wave brain state unravels the functional connectivity and the biological substrate of the rodent dorsolateral and dorsomedial striatum, demonstrating its organization in two non-overlapping circuits.

Refine your results by:

Type
Research categories