Retrograde tracing of the neural circuits that control movement of the jaw and tongue reveals how shared premotor neurons help to ensure coordinated muscle activity.

A comprehensive synapse-level analysis of a fly central-brain region has led to the identification of molecules that are necessary for mediating the normal density of connections.

A lack of ADAM10-mediated shedding increases prion protein levels at the plasma membrane and promotes the generation of pathological prion proteins, which accelerates prion disease in mice.

By employing high-field fMRI to measure connectivity with the hippocampus and adjacent parahippocampal structures within the medial temporal lobe, it is shown that the entorhinal cortex can be divided into anterior-lateral and posterior-medial subregions.

Dopamine neurons projecting to different targets receive a similar set of inputs, rather than forming reciprocal connections, whereas those projecting to the posterior striatum receive a distinct set of inputs.

Cholinergic system play an important role in waking-to-sleep cycles and in sleep stabilization.

A novel transposon-based enhancer trap screen in mice permits high throughput development of highly restricted driver strains targeting specific neuronal cell types.

Syntaxin 4 regulates retrograde signaling in the postsynaptic compartment at Drosophila synapses by controlling trafficking of Neuroligin and Synaptotagmin 4 cargo.

Whole-brain mapping of the basal forebrain circuits reveals a connection diagram with highly convergent inputs and divergent outputs.

Filamin, by recruiting a signaling complex to the postsynapse, orchestrates the correct formation and growth of postsynaptic membranes and localization of glutamate receptor subunits.