Jennifer N Jahncke, Daniel S Miller ... Kevin M Wright
Loss of functional dystroglycan disrupts the formation and function of CCK+/CB1R+ inhibitory synapses in hippocampal CA1, resulting in reduced seizure thresholds in mouse models of dystroglycanopathy.
Nerve tracing and behavioral studies in tumor-bearing mice together with transcriptional and functional analysis reveal cancer-induced central and peripheral neuronal alterations that influence behavior.
Jaebin Kim, Edwin Bustamante ... Scott H Soderling
Presynaptic Rac1 inhibition in the hippocampus impairs spatial working memory, potentially by modulating the synaptic cytoskeleton and kinase-mediated phosphorylation of key synaptic vesicle proteins.
Excitatory and inhibitory neurons in the mouse superior colliculus receive comparably strong inputs from retinal ganglion cells, in contrast to the thalamocortical system.
Newly developed methods to genetically target cerebrospinal fluid-contacting neurons reveal unique caudorostrally extended projections and recurrent connections in the spinal motor circuitry to control locomotion in mice.