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    1. Neuroscience

    Variability in the Munc13-1 content of excitatory release sites

    Maria Rita Karlocai, Judit Heredi ... Zoltan Nusser
    Different numbers of Munc13-1 molecules build up the specialized regions of the presynaptic plasma membrane called the release sites.
    1. Neuroscience

    Circuit organization of the excitatory sensorimotor loop through hand/forelimb S1 and M1

    Naoki Yamawaki, Martinna G Raineri Tapies ... Gordon MG Shepherd
    Cell-type-specific circuit analysis reveals a highly polysynaptic pattern of excitatory feedforward connections along the somatosensory-to-motor loop, from cuneate via VPL thalamus to S1 and M1 cortex and corticospinal neurons.
    1. Neuroscience

    Toolkits for detailed and high-throughput interrogation of synapses in C. elegans

    Maryam Majeed, Haejun Han ... Hang Lu
    An imaging pipeline together with a collection of transgenic nematode strains provide a strategy to visualize and properly quantify synaptic connectivity in the C. elegans brain.
    1. Neuroscience

    A septo-hypothalamic-medullary circuit directs stress-induced analgesia

    Devanshi Piyush Shah, Pallavi Raj Sharma ... Arnab Barik
    Acute stress and anxiety can suppress pain, here we reveal a multi-nodal circuit in the brain that connects the two.
    1. Neuroscience

    Synaptic organization of the Drosophila antennal lobe and its regulation by the Teneurins

    Timothy J Mosca, Liqun Luo
    A comprehensive synapse-level analysis of a fly central-brain region has led to the identification of molecules that are necessary for mediating the normal density of connections.
    1. Neuroscience

    Monosynaptic tracing maps brain-wide afferent oligodendrocyte precursor cell connectivity

    Christopher W Mount, Belgin Yalçın ... Michelle Monje
    Oligodendrocyte precursor cells receive brain-wide, circuit-specific intracortical, coritcocortical and thalamocortical synaptic inputs.
    1. Developmental Biology
    2. Neuroscience

    Kit Ligand and Kit receptor tyrosine kinase sustain synaptic inhibition of Purkinje cells

    Tariq Zaman, Daniel Vogt ... Michael R Williams
    The transmembrane protein Kit Ligand and the Kit receptor tyrosine kinase are required for synapse function between specific cell types in the mouse cerebellum.
    1. Medicine

    An atlas of brain-bone sympathetic neural circuits in mice

    Vitaly Ryu, Anisa Azatovna Gumerova ... Mone Zaidi
    Central SNS outflow sites originating from 87 brain nuclei and sub-nuclei in six brain divisions innervate bone.
    1. Neuroscience

    A brainstem circuit controls cough-like airway defensive behaviors in mice

    Xiaoshan Xu, Xiupeng Nie ... Fujun Luo
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Neuroscience

    The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling

    Kathryn P Harris, Yao V Zhang ... J Troy Littleton
    Syntaxin 4 regulates retrograde signaling in the postsynaptic compartment at Drosophila synapses by controlling trafficking of Neuroligin and Synaptotagmin 4 cargo.