69 results found
    1. Biochemistry and Chemical Biology
    2. Ecology

    ABC transporter functions as a pacemaker for sequestration of plant glucosides in leaf beetles

    Anja S Strauss et al.
    A transport protein enables leaf beetle larvae to take up and store plant toxins and use them as part of their own defense strategy.
    1. Developmental Biology
    2. Evolutionary Biology

    Dual mode of embryonic development is highlighted by expression and function of Nasonia pair-rule genes

    Miriam I Rosenberg et al.
    Pair-rule genes in the wasp Nasonia function as in Drosophila in patterning anterior segments, and similar to ancestral insects in patterning posterior segments, illustrating a mixed-mode transition state between short and long germ embryogenesis.
    1. Evolutionary Biology

    Evolution of insect olfactory receptors

    Christine Missbach et al.
    Insect specific olfactory receptors are not an adaptation to a terrestrial insect lifestyle, but evolved later in insect evolution.
    1. Biochemistry and Chemical Biology

    Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks

    Suwen Zhao et al.
    Genome neighborhood networks provide an efficient large-scale approach to mine metabolic pathway context for entire families of proteins and enzymes.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Recurrent loss of CenH3 is associated with independent transitions to holocentricity in insects

    Ines A Drinnenberg et al.
    CenH3, the defining component of centromeres in almost all eukaryotes, was independently lost in four insect lineages that transitioned from monocentricity to holocentricity.
    1. Biochemistry and Chemical Biology
    2. Human Biology and Medicine

    B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of α-dystroglycan

    Jeremy L Praissman et al.
    The correct enzymatic activity of a previously misnamed enzyme is defined, placing the enzyme upstream of LARGE in building functional O-mannose structures on α-dystroglycan that are disrupted in multiple forms of congenital muscular dystrophy.
    1. Developmental Biology
    2. Immunology and Inflammation

    The extraembryonic serosa is a frontier epithelium providing the insect egg with a full-range innate immune response

    Chris G C Jacobs et al.
    Contrary to the current perception, insect eggs are very capable of defending themselves against pathogens.
  1. Understanding the evolution of defence: an interview with Maurijn van der Zee

    Maurijn van der Zee is a tenure-track assistant professor at Leiden University in the Netherlands. His primary interest is to understand the genetic and developmental mechanisms that underlie evolutionary change in animals, but recently he has been exploring a new field: innate immunity in insects. Six months ago he became a father for the first time ‘to a beautiful daughter’. His first PhD student also graduated very recently: he says that this also felt a bit like becoming a father. Maurijn also enjoys writing popular science articles for the Dutch press and giving public lectures.
    1. Biochemistry and Chemical Biology

    Thermodynamic evidence for a dual transport mechanism in a POT peptide transporter

    Joanne L Parker et al.
    Two thermodynamically distinct transport mechanisms operating within the same binding site explains the remarkable promiscuity of POT family transporters towards peptide and drug ligands.
    1. Structural Biology and Molecular Biophysics

    Recognition of the small regulatory RNA RydC by the bacterial Hfq protein

    Daniela Dimastrogiovanni et al.
    The regulatory RNA RydC binds to Hfq to make an effector complex for the recognition of targeted mRNA in the regulation of genetic information.

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