A new device enables researchers to use and recycle extracellular electrodes (e.g. Neuropixels) for high-yield recordings during freely moving mouse experiments.

Engineered T cell receptors enable targeted immunotherapy with a reduced risk of harmful autoimmunity.

The polarity protein crumbs controls apical secretion and the architecture of the apical domain by modulating PI(4,5)P₂ levels and the organization of apical Rab6-, Rab11-, and Rab30-dependent trafficking.

The zebrafish has been established as a genetic and molecular model for the blood-brain barrier.

Caenorhabditis elegans behavioral response to a mechanosensory signal depends on both the temporal properties of the signal, such as its rate of change, and the animal's current behavior state.

A new multi camera imaging platform simultaneously captures large-area, high-resolution video of unconstrained small model organisms and provides behavioral measurements that span multiple spatial scales.

Three-dimensional imaging and automated, brain-wide cell counting yield new insight into the diversity of neurons that connect the brain to the spinal cord and their different sensitivity to spinal cord damage.

Pre-complexation of vinculin with talin’s R8 domain facilitates nascent adhesion maturation by unfolding talin, increasing vinculin binding, and thereby transmitting traction forces to the environment.