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    1. Computational and Systems Biology

    Distributing tasks via multiple input pathways increases cellular survival in stress

    Alejandro A Granados, Matthew M Crane ... Peter S Swain
    Single-cell experiments and mathematical modelling show that cellular signalling networks are vulnerable to trade-offs in speed versus accuracy, but that these vulnerabilities can be overcome by distributing the two tasks to different, although interacting, subnetworks.
    1. Cell Biology

    β-Arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor

    Carole Daly, Akim Abdul Guseinov ... Bianca Plouffe
    The vasopressin type 2 receptor promotes dual Gαs and Gαq/11 signaling at early endosomes in β-arrestin-dependent and -independent manners.
  1. Innovation Sprint 2019

    Innovation Sprint 2019: Project roundup

    From web tools to drive forward research discovery, citation and evaluation, to literature curation and knowledge extraction, we showcase the projects developed at this year’s Innovation Sprint.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Inducible mechanisms of disease tolerance provide an alternative strategy of acquired immunity to malaria

    Wiebke Nahrendorf, Alasdair Ivens, Philip J Spence
    Malaria remodels the spleen to imprint tolerance and reduce pathology in subsequent infections.
  2. Living Science: In numbers we trust?

    Eve Marder
    Scientists go to great lengths to ensure that data are collected and analysed properly, so why do they apply different standards to data about the number of times research papers have been cited and viewed?
    1. Ecology
    2. Genetics and Genomics

    Education and Outreach: March Mammal Madness and the power of narrative in science outreach

    Katie Hinde, Carlos Eduardo G Amorim ... Christopher N Anderson
    Hypothetical battles between animals can be used to interest the general public in biology.
    1. Computational and Systems Biology

    Point of View: Data science for the scientific life cycle

    Daphne Ezer, Kirstie Whitaker
    Each stage of the scientific life cycle stands to benefit from the introduction of data science techniques.
  3. Living Science: Grandmother elephants

    Eve Marder
    As new technology makes it possible to perform experiments that were unimaginable a decade ago, Eve Marder argues that we can still learn from the past.
  4. Meta-Research: Systemic racial disparities in funding rates at the National Science Foundation

    Christine Yifeng Chen, Sara S Kahanamoku ... Justin Hosbey
    White principal investigators applying to the National Science Foundation are consistently funded at higher rates than most non-white PIs.
  5. Point of View: How should novelty be valued in science?

    Barak A Cohen
    An over-emphasis on novelty is having detrimental effects on science.