70 results found
    1. Neuroscience

    Associative memory neurons of encoding multi-modal signals are recruited by neuroligin-3-mediated new synapse formation

    Yang Xu, Tian-liang Cui ... Jin-Hui Wang
    The coactivity of cortical neurons in associative learning recruits them as associative memory cells based on their synapse interconnections by neuroligin-3-mediated synapse formation, which endorses the first order and the second order of associative memory.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural basis for an unprecedented enzymatic alkylation in cylindrocyclophane biosynthesis

    Nathaniel R Braffman, Terry B Ruskoski ... Emily P Balskus
    The X-ray crystal structure of the unusual carbon–carbon bond-forming biosynthetic enzyme CylK reveals a unique biochemical strategy for selective alkyl halide activation and substitution.
    1. Neuroscience

    A connectome of a learning and memory center in the adult Drosophila brain

    Shin-ya Takemura, Yoshinori Aso ... Louis K Scheffer
    Connectomic analysis in the fly's (Drosophila) learning and memory center identifies unique circuit motifs that have not been anticipated by over 30 years of extensive anatomical, experimental and theoretical studies.
    1. Cell Biology

    Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions

    Sagnik Pal, Yangyang Su ... Mark Richards
    Not revised
    Reviewed Preprint v1
    • Useful
    • Inadequate
    1. Neuroscience

    Nitric oxide acts as a cotransmitter in a subset of dopaminergic neurons to diversify memory dynamics

    Yoshinori Aso, Robert P Ray ... Gerald M Rubin
    The interplay of nitric oxide and dopamine specialize one memory unit in a fly brain in predicting the value of odors based only on recent experience.
    1. Neuroscience

    Sigh generation in preBötzinger Complex

    Yan Cui, Evgeny Bondarenko ... Jack L Feldman
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Neuroscience

    Circadian programming of the ellipsoid body sleep homeostat in Drosophila

    Tomas Andreani, Clark Rosensweig ... Ravi Allada
    The circadian clock gates sleep drive by modulating sleep homeostat neurons.
    1. Stem Cells and Regenerative Medicine

    Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors

    Lampros Mavrommatis, Hyun-Woo Jeong ... Holm Zaehres
    Skeletal muscle organoids differentiated from human pluripotent stem cells offer a system for investigating myogenesis and satellite cell development with translational potential for muscular dystrophy modeling and therapy development.
    1. Neuroscience

    Visual projection neurons in the Drosophila lobula link feature detection to distinct behavioral programs

    Ming Wu, Aljoscha Nern ... Gerald M Rubin
    Neurons called lobula columnar cells help fruit flies respond appropriately to specific visual cues, such as those signaling an approaching predator.

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