Single measurements of baseline salivary and plasmatic oxytocin are not sufficiently reliable to provide valid trait markers of the physiology of the oxytocin system in humans.

The evolutionary loss of the main enzyme required for ketone body biosynthesis suggests that alternative strategies to provide energy for large brains during fasting evolved repeatedly in mammals.

A machine-learning approach is used to predict 1.35 million interactions for 85% of the human proteome.

Genetic effects on body weight in mice are highly heterogeneous, dynamic, and nonlinear with respect to genomic background, age, and diet.

The cancer drug vemurafenib has potent off-target effects on JNK signaling that contribute to the development of squamous cell carcinomas in humans and in mice.

Risk factors for SARS-CoV-2 infection in healthcare workers included caring for Covid-19 patients, Black or Asian ethnicity, and Covid-19-positive household contacts, whereas a bundle of PPE-related measures protected ICU staff.

Quantitative genetics approaches using Caenorhabditis elegans facilitate the discovery of a novel arsenic toxicity mechanism.

Neurodevelopmental critical periods act to integrate activity to encode homeostatic set points that remain fixed thereafter.

Combined analyses of publicly available population-level variant data and detailed individual-level clinical data can be used to quantify the clinical impact of new SARS-CoV-2 variants in different settings.

Mother brain shows special sensitivity to social moments of mother-infant synchrony, compared to other caregiving experiences, through enhanced activation across the caregiving network, response to oxytocin administration, and temporal consistency.