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    1. Neuroscience

    Uncertainty-based inference of a common cause for body ownership

    Marie Chancel, H Henrik Ehrsson, Wei Ji Ma
    Behavioral and computational results show that the perception of our body as our own depends on Bayesian probabilistic reasoning that take into account the variations in sensory uncertainty when integrating visual and somatosensory cues.
    1. Evolutionary Biology
    2. Plant Biology

    Independent evolution of ancestral and novel defenses in a genus of toxic plants (Erysimum, Brassicaceae)

    Tobias Züst, Susan R Strickler ... Georg Jander
    A gain-of-function in a new chemical defense resulted in no trade-offs and and independent evolution between novel and ancestral defenses, suggesting low redundancy among different defensive chemicals.
    1. Neuroscience

    Mapping responses to focal injections of bicuculline in the lateral parafacial region identifies core regions for maximal generation of active expiration

    Annette Pisanski, Mitchell Prostebby ... Silvia Pagliardini
    Multivariate analysis of respiratory cycle shows that GABAergic disinhibition in the rostral regions of the lateral parafacial area is linked to the most significant and enduring changes in active expiration.
    1. Neuroscience

    Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions

    Mingzheng Wu, Samuel Minkowicz ... Yevgenia Kozorovitskiy
    Interconnected ventral tegmental area and medial prefrontal cortex circuits causally link dopamine dynamics, aversive learning, and the effects of a promising rapidly acting antidepressant ketamine.
    1. Cell Biology
    2. Plant Biology

    SnRK1-triggered switch of bZIP63 dimerization mediates the low-energy response in plants

    Andrea Mair, Lorenzo Pedrotti ... Markus Teige
    The transcription factor bZIP63 is a key regulator of the starvation response in the model plant Arabidopsis thaliana and is directly targeted by the kinase SnRK1.
    1. Neuroscience

    I-Spin live, an open-source software based on blind-source separation for real-time decoding of motor unit activity in humans

    Julien Rossato, François Hug ... Simon Avrillon
    I-Spin enables researchers to decode motor unit firings from surface and intramuscular electromyographic signals in real time.
    1. Neuroscience

    Neural assemblies uncovered by generative modeling explain whole-brain activity statistics and reflect structural connectivity

    Thijs L van der Plas, Jérôme Tubiana ... Georges Debrégeas
    A data-driven network model offers an interpretable and physiologically sound description of the whole-brain spontaneous neural activity of zebrafish larvae.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Structural state recognition facilitates tip tracking of EB1 at growing microtubule ends

    Taylor A Reid, Courtney Coombes ... Melissa K Gardner
    EB1 targeting to growing microtubule plus-ends is facilitated by tapered microtubule tip structures.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure

    KM Rifat Faysal, James C Walsh ... Till Böcking
    The anti-HIV drug lenacapavir breaks the HIV capsid by stabilising regions of low curvature at the expense of maintaining a closed shell, leading to loss of viral DNA synthesis and inhibition of infection.
    1. Neuroscience

    Human and macaque pairs employ different coordination strategies in a transparent decision game

    Sebastian Moeller, Anton M Unakafov ... Igor Kagan
    Using novel approach to study real-time social interactions shows that mutual action visibility facilitates static and dynamic coordination in both species, but whereas humans employ dynamic turn-taking to equalize rewards, macaques, after training with a human, compete between themselves.