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    1. Microbiology and Infectious Disease
    2. Neuroscience

    Enteric glia regulate Paneth cell secretion and intestinal microbial ecology

    Aleksandra Prochera, Anoohya N Muppirala ... Meenakshi Rao
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology

    A ‘torn bag mechanism’ of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes)

    Tamás Visnovitz, Dorina Lenzinger ... Edit I Buzas
    A novel 'torn bag mechanism' is described for the release of LC3 positive and negative small extracellular vesicles (exosomes) from amphiectosomes.
    Version of Record
    Short Report
    • Important
    • Compelling
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Soluble immune mediators orchestrate protective in vitro granulomatous responses across Mycobacterium tuberculosis complex lineages

    Ainhoa Arbués, Sarah Schmidiger ... Damien Portevin
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Microbiology and Infectious Disease

    Multi-omics investigation of spontaneous T2DM macaque reveals gut microbiota promote T2DM by up-regulating the absorption of excess palmitic acid

    Xu Liu, Shengzhi Yang ... Jing Li
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology

    Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in obesity

    Dan Wu, Venkateswararao Eeda ... Weidong Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    The Mycobacterium ulcerans toxin mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane to drive skin necrosis

    Louise Tzung-Harn Hsieh, Belinda S Hall ... Rachel E Simmonds
    The secreted toxin mycolactone has severe effects on the cells lining blood vessels that will play a critical role in the development of swelling in Buruli ulcer disease.
    1. Microbiology and Infectious Disease

    Transcriptional antitermination integrates the expression of loci of diverse phage origin in the chimeric Bartonella Gene Transfer Agent BaGTA

    Aleksandr Korotaev, Quirin Niggli, Christoph Dehio
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Physics of Living Systems

    Emergence of alternative stable states in microbial communities undergoing horizontal gene transfer

    Juken Hong, Wenzhi Xue, Teng Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease

    DNA Methylome Regulates Virulence and Metabolism in Pseudomonas syringae

    Jiadai Huang, Fang Chen ... Xin Deng
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Genetics and Genomics

    The PRC2.1 subcomplex opposes G1 progression through regulation of CCND1 and CCND2

    Adam D Longhurst, Kyle Wang ... David P Toczyski
    An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.
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