424 results found
    1. Cell Biology
    2. Plant Biology

    SnRK1-triggered switch of bZIP63 dimerization mediates the low-energy response in plants

    Andrea Mair et al.
    The transcription factor bZIP63 is a key regulator of the starvation response in the model plant Arabidopsis thaliana and is directly targeted by the kinase SnRK1.
    1. Cell Biology

    The GTPase IFT27 is involved in both anterograde and retrograde intraflagellar transport

    Diego Huet et al.
    A small GTPase within the flagellum can participate in the control of transport from the base to the tip of the flagellum, and back again.
  1. Early-career researcher travel grants: Next four authors selected

    Four eLife authors will receive a grant of up to $1,000 to support their attendance and presentation at a meeting of their choice.
    1. Developmental Biology
    2. Neuroscience

    Robo2 regulates synaptic oxytocin content by affecting actin dynamics

    Savani Anbalagan et al.
    Real-time monitoring of oxytocin-loaded vesicles and synaptic actin dynamics in zebrafish reveal that Slit3-Robo2-Cdc42 signalling maintains steady-state levels of mature oxytocin neuropeptide readily primed to be secreted upon physiological demand.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Electron tomography visualization of HIV-1 fusion with target cells using fusion inhibitors to trap the pre-hairpin intermediate

    Mark S Ladinsky et al.
    Visualization of HIV-1 fusion by trapping the prehairpin intermediate.
    1. Cell Biology
    2. Developmental Biology

    Mitochondrial fusion is required for spermatogonial differentiation and meiosis

    Grigor Varuzhanyan et al.
    Mitochondrial fusion enables a metabolic transition during spermatogenesis.
    1. Cell Biology
    2. Developmental Biology

    Growth cone-localized microtubule organizing center establishes microtubule orientation in dendrites

    Xing Liang et al.
    In Caenorhabditis elegans, dendrites establish their unique microtubule polarity by localizing an organizing center behind the growing tip.
    1. Immunology and Inflammation
    2. Neuroscience

    Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain

    Jeremy Carlos Burns et al.
    Two novel subsets of microglia identified by their unique autofluorescence profiles differ in their subcellular organization, proteomic signatures and in their response to aging and lysosomal dysfunction.
    1. Microbiology and Infectious Disease

    A divergent cyclin/cyclin-dependent kinase complex controls the atypical replication of a malaria parasite during gametogony and transmission

    Aurélia C Balestra et al.
    Multiple steps of the atypical cell cycles underlying Plasmodium gametogony are controlled by a divergent cyclin/cyclin-dependent complex.
    1. Cell Biology
    2. Developmental Biology

    Protein phosphatase 1 activity controls a balance between collective and single cell modes of migration

    Yujun Chen et al.
    Protein phosphatase 1 activity promotes cohesive collective cell migration by restricting actomyosin contractility to the periphery of the collective and maintaining proper cadherin–catenin complex protein levels at cell–cell junctions.

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