Browse the search results

There is no relationship between the demographic susceptibility to extinction and the estimated extinction chronology among Sahul’s megafauna, suggesting that human choices, a species’ ecological requirements, and/or random climate variation instead determined the extinction chronology.

The diversification of hand bones in mammals was much more dynamic than those of the proximal and intermediate forearm, involving higher morphological diversity, stronger integration, and greater evolutionary lability at distal structures.

Cytoplasmic bodies sequester important abscission machinery to delay completion of cytokinesis in response to mitotic errors.

Proteolytic activation of a sodium-permeable channel that aids in gas exchange and fluid homeostasis likely evolved at the water to land transition in vertebrates.

Fluorescently-tagged profilin-1 behaves similar to the tag-free protein in biochemical and cell-based assays.

Comparing the white-footed deermouse with mice and rats in an inflammation model reveals a means for the observed infection tolerance in this key animal reservoir for several human diseases.

Purinergic keratinocyte-to-sensory neuron signaling is a ubiquitous amplification mechanism that is required for normal mechanical, cold, and heat sensation in vivo.

A rigorous and transparent evaluation of mesenchymal stem cell therapy for sepsis suggests it may be efficacious, although the strength of these findings is tempered by threats to validity in the studies that were included.

This review considers the evolutionary processes and physiological mechanisms that maintain or end pregnancy in mammals to formulate general, testable theoretical models that provide insights into the biology of parturition.