Discovery of a novel mode of sexual reproduction, termed pseudosexual reproduction, in fungi where both parents are required for mating but only one contributes to the meiotic progeny, similar to hybridogenesis in animals.
Meiosis and differentiation of basidium, a defining sexual structure of the phylum Basidiomycota, are genetically integrated by a shared regulatory program to ensure the formation of infectious meiospores in Cryptococcus neoformans.
Andrew Ryan Passer, Shelly Applen Clancey ... Marco A Coelho
A novel form of self-fertility evolved in Cryptococcus depauperatus, a close relative to the human pathogenic Cryptococcus species, in which sexual development is attained by self-signaling of a cognate pheromone and pheromone-receptor pair.
R Blake Billmyre, Shelly Applen Clancey, Joseph Heitman
Eukaryotic pathogens, like Cryptococcus deuterogattii, can use elevated mutation rates to more rapidly adapt to stresses, such as drug challenges, but at the cost of lower fitness in less stressful environments.
The courtship master gene fruitless tunes functional flexibility of courtship circuitry during development instead of switching on its function as conventionally viewed.
This Pride Month, we restate our commitment to supporting the LGBTQ+ community and working to help shape research culture to be more equitable, diverse and inclusive.
Allison Schad, Rebekah L Layton ... Jeanette Gowen Cook
Biomedical doctoral students and those from historically excluded groups exhibit higher rates of mental distress, which worsened in 2020 for some populations.