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An interaction between the ion channel ASIC1a and the protein RIP1 is responsible for neuronal death caused by tissue acidosis.

Naturalistic animal behavior exhibits a complex organization in the temporal domain, whose variability stems from hierarchical, contextual, and stochastic sources and can be naturally explained in terms of metastable attractor models.

Single-cell mRNA sequencing shows that the impact of infection with influenza virus varies dramatically from one cell to another.

Molecular clocks that are robust to external fluctuations are vulnerable to internal fluctuations and vice versa.

T2N, a novel interface between Matlab, TREES toolbox and NEURON, was used to generate compartmental models that reproduce the electrophysiology of dentate granule cells over a multitude of species, experimental conditions and developmental stages.

Recurrent interactions in the optic tectum underlie activity-dependent changes in network state that account for variability in sensory encoding and behavior.

Analysis of published studies reveals that flagellates and ciliates separately exhibit log-normal distributions of swimming speeds, and rescaling by the mean speed of each collapses them to a universal relationship.

Orthologous proteins that continuously maintain the same molecular function do not usually diverge beyond a certain level of sequence and structural similarity.

Computational analysis of MNase-seq data reveals that alternatively positioned nucleosomes are prevalent in both yeast and human cells and create significant heterogeneity within cell populations.

Mapping spike patterns from a small identified circuit reveals the diversity and complexity of circuit dynamics across animals and in response to perturbations.