7 results found
    1. Cell Biology
    2. Evolutionary Biology

    Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism

    Matteo Fumagalli, Stephane M Camus ... Frances M Brodsky
    Natural selection shaped CHC22 clathrin genetic variation in humans with different diets and potentially influenced the human insulin response.
    1. Ecology
    2. Evolutionary Biology

    Tooth fracture frequency in gray wolves reflects prey availability

    Blaire Van Valkenburgh, Rolf O Peterson ... John A Vucetich
    Despite risks of infection and reduced fitness, tooth fracture frequency in gray wolves increases rapidly when prey are scarce because they must consume carcasses more completely.
    1. Biochemistry and Chemical Biology

    Skd3 (human ClpB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations

    Ryan R Cupo, James Shorter
    Skd3 (human ClpB) is a potent ATP-dependent mitochondrial protein disaggregase that is activated by the rhomboid protease, PARL, and inactivated by MGCA7-linked mutations.
    1. Evolutionary Biology
    2. Genetics and Genomics

    High-quality carnivoran genomes from roadkill samples enable comparative species delineation in aardwolf and bat-eared fox

    Rémi Allio, Marie-Ka Tilak ... Frédéric Delsuc
    High-quality genomes can be obtained from roadkill samples and used in population genomics for species delimitation with conservation implications.
    1. Evolutionary Biology
    2. Genetics and Genomics

    A paternal bias in germline mutation is widespread in amniotes and can arise independently of cell division numbers

    Marc de Manuel, Felix L Wu, Molly Przeworski
    A paternal bias in germline mutation is seen throughout amniotes and may be explained by sex differences in DNA damage and repair after primordial germ cell specification.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Remodeling of skeletal muscle myosin metabolic states in hibernating mammals

    Christopher TA Lewis, Elise G Melhedegaard ... Julien Ochala
    During hibernation, animals remodel the structure of their relaxed muscle via a protein called myosin and this enables vast temperature changes.
    1. Ecology

    Different coexistence patterns between apex carnivores and mesocarnivores based on temporal, spatial, and dietary niche partitioning analysis in Qilian Mountain National Park, China

    Wei Cong, Jia Li ... Yuguang Zhang
    Spatial segregation is identified as the primary mechanism facilitating the coexistence of apex and mesocarnivores in the Qilian Mountain National Park, China.

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