142 results found
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Potential impact of outpatient stewardship interventions on antibiotic exposures of common bacterial pathogens

    Christine Tedijanto et al.
    Antibiotic stewardship in the outpatient setting can substantially reduce exposures of potential pathogens to common antibiotics, and complementary efforts are needed to reduce remaining exposures that occur in 'necessary' contexts.
    1. Cancer Biology

    Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies

    Ana Rita Pombo Antunes et al.
    The heterogeneity of immune cell types in glioblastoma tumors depends on the tumor's genetic make-up and treatment status and is an incompletely mined source of novel therapeutic targets.
    1. Immunology and Inflammation

    Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells

    Rebeca Jimeno et al.
    The tissue environment shapes the lipid recognition capacity of natural killer T cells.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Broadly neutralizing human antibodies against dengue virus identified by single B cell transcriptomics

    Natasha D Durham et al.
    Identification of viral and host determinants of broadly neutralizing antibodies targeting a new epitope on dengue virus that can be used to guide vaccine design.
    1. Epidemiology and Global Health

    Risk factors for asthma among schoolchildren who participated in a case-control study in urban Uganda

    Harriet Mpairwe et al.
    Asthma risk among schoolchildren increases depending on area of residence in early life, from rural to town to city, and this risk increases further with other known risk factors.
    1. Microbiology and Infectious Disease

    Rhabdo-immunodeficiency virus, a murine model of acute HIV-1 infection

    Rachel A Liberatore et al.
    A new animal model permits the in vivo study of HIV-1 entry, as well as the elicitation and antiviral activity of antibodies, in a genetically manipulatable host.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    An evolutionary recent IFN/IL-6/CEBP axis is linked to monocyte expansion and tuberculosis severity in humans

    Murilo Delgobo et al.
    Mycobacterium tuberculosis exploits an IFN/IL6/CEBP axis linked to monocyte expansion in humans.
    1. Physics of Living Systems

    Phylodynamic theory of persistence, extinction and speciation of rapidly adapting pathogens

    Le Yan et al.
    A model of pathogen co-evolving with host population continuously acquiring immunity is used to identify evolutionary parameters allowing pathogen population to persist without going extinct or splitting into independent lineages.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Complement and CD4+ T cells drive context-specific corneal sensory neuropathy

    Derek J Royer et al.
    The complement pathway can contribute to corneal sensation loss and nerve damage during ocular surface inflammation.
    1. Epidemiology and Global Health

    Seasonal variation and etiologic inferences of childhood pneumonia and diarrhea mortality in India

    Daniel S Farrar et al.
    Nationally-representative verbal autopsies can be linked to seasonal patterns, clinical syndromes, and climate regions to describe novel insights regarding the microbiologic etiologies of childhood pneumonia and diarrhea in India.

Refine your results by:

Type
Research categories