444 results found
    1. Neuroscience

    Network oscillation rules imposed by species-specific electrical coupling

    Stefanos Stagkourakis et al.
    An unexpected species difference in electrical coupling of analogous neuroendocrine dopamine neurons in rats and mice reveals a role for gap junction connectivity as a band-pass filter for oscillation frequency in neural networks.
    1. Developmental Biology
    2. Neuroscience

    Slow oscillation-spindle coupling predicts enhanced memory formation from childhood to adolescence

    Michael A Hahn et al.
    An individualized cross-frequency coupling approach identified slow oscillation-spindle coupling strength as a novel mechanism that mediates memory formation during cortical maturation.
    1. Neuroscience

    Vacillation, indecision and hesitation in moment-by-moment decoding of monkey motor cortex

    Matthew T Kaufman et al.
    Trial-by-trial analysis of neuronal activity in monkeys performing a decision-making task reveals the neural correlates of behaviours including wavering, hesitation and sudden changes of mind.
    1. Neuroscience

    Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves

    Miriam Schwalm et al.
    Locally recorded calcium events related to slow wave activity show a global cortical fMRI BOLD correlate, establishing a direct relation between a basic neurophysiological signal and the macroscopic perspective of pre-clinical fMRI.
    1. Computational and Systems Biology
    2. Developmental Biology

    A balance of positive and negative regulators determines the pace of the segmentation clock

    Guy Wiedermann et al.
    Computational modelling together with experimental manipulation indicate that the stability and turnover of activated Notch is inextricably linked to the regulation of the pace of segmentation clock gene expression in the presomitic mesoderm.
    1. Neuroscience

    Impaired fast-spiking interneuron function in a genetic mouse model of depression

    Jonas-Frederic Sauer et al.
    Truncated Disrupted-in-schizophrenia 1 (Disc 1) ablates signaling of parvalbumin-expressing interneurons in the prefrontal cortex and underlies depression-related behaviour in mice.
    1. Neuroscience

    Excitatory motor neurons are local oscillators for backward locomotion

    Shangbang Gao et al.
    Motor neurons are rhythm generators for backward locomotion.
    1. Computational and Systems Biology
    2. Neuroscience

    Interneuronal mechanisms of hippocampal theta oscillations in a full-scale model of the rodent CA1 circuit

    Marianne J Bezaire et al.
    Spontaneous theta oscillations and interneuron-specific phase preferences emerge spontaneously in a full-scale model of the isolated hippocampal CA1 subfield, corroborating and extending recent experimental findings.
    1. Computational and Systems Biology
    2. Neuroscience

    Noise promotes independent control of gamma oscillations and grid firing within recurrent attractor networks

    Lukas Solanka et al.
    Random fluctuations in neuronal firing may enable a single brain region, the medial entorhinal cortex, to perform distinct roles in cognition (by generating gamma waves) and spatial navigation (by producing a grid cell map).
    1. Neuroscience

    Learning improves decoding of odor identity with phase-referenced oscillations in the olfactory bulb

    Justin Losacco et al.
    Tetrode recordings show that the amplitude of gamma oscillations encodes for information on contextual odorant identity when observed at the peak phase of the theta oscillation in the olfactory bulb.

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