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    1. Immunology and Inflammation

    Nociceptor Neurons Control Pollution-Mediated Neutrophilic Asthma

    Jo-Chiao Wang, Theo Crosson ... Sebastien Talbot
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Leptin suppresses development of GLP-1 inputs to the paraventricular nucleus of the hypothalamus

    Jessica E Biddinger, Roman M Lazarenko ... Richard Simerly
    Leptin acts cell autonomously on brainstem neurons that express GLP-1 to suppress development of excitatory viscerosensory inputs to the hypothalamus.
    1. Neuroscience

    Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure

    Virginie Mansuy-Aubert, Laurent Gautron ... Joel K Elmquist
    In sensory neurons, the receptors LXRα and LXRβ sense dietary-derived molecules to regulate whole body energy expenditure, and present a possible target for new anti-obesity agents.
    1. Medicine

    Chemogenetics defines a short-chain fatty acid receptor gut–brain axis

    Natasja Barki, Daniele Bolognini ... Graeme Milligan
    The G protein-coupled receptors FFA2 and FFA3, activated by short-chain fatty acids, are mediators of a gut–brain axis.
    1. Neuroscience

    Live calcium and mitochondrial imaging in the enteric nervous system of Parkinson patients and controls

    An-Sofie Desmet, Carla Cirillo ... Pieter Vanden Berghe
    In contrast to previous post-mortem or fixed tissue histochemical reports, live calcium and mitochondrial imaging data suggest that the enteric nervous system is not generally affected in Parkinson's disease patients.
    1. Medicine
    2. Neuroscience

    Deciphering the neural signature of human cardiovascular regulation

    Jorge Manuel, Natalia Färber ... Florian Beissner
    At least three hypothalamic subsystems are involved in cardiovascular regulation in humans.
    1. Cancer Biology
    2. Neuroscience

    Stimulation of hypothalamic oxytocin neurons suppresses colorectal cancer progression in mice

    Susu Pan, Kaili Yin ... Guo Zhang
    Assessments using chemogenetic and pharmacological approaches reveal that modulation of the activities of oxytocin neurons in the hypothalamus of the central nervous system could inhibit colorectal cancer progression in mice.
    1. Microbiology and Infectious Disease

    Lactococcus lactis NCDO2118 exerts visceral antinociceptive properties in rat via GABA production in the gastro-intestinal tract

    Valérie Laroute, Catherine Beaufrand ... Muriel Cocaign-Bousquet
    Generally recognised as safe GABA-producing L. lactis strains could be considered as future therapeutic agents for the management of visceral pain and the anxious profile of IBS patients.
    1. Neuroscience

    NaV1.1 is essential for proprioceptive signaling and motor behaviors

    Cyrrus M Espino, Cheyanne M Lewis ... Theanne N Griffith
    The voltage-gated sodium channel Nav1.1 is identified as an essential component of the proprioceptive transmission machinery that is required in vivo for normal motor behavior.
    1. Medicine
    2. Neuroscience

    Tiered sympathetic control of cardiac function revealed by viral tracing and single cell transcriptome profiling

    Sachin Sharma, Russell Littman ... Olujimi A Ajijola
    Cardiac-specific neurons residing in stellate ganglia comprised of three subsets of neurons based upon their transcriptomic and neurochemical properties and modulates cardiac sympathetic control.